An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5.
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| Title: | An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5. |
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| Authors: | Storm N; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Lo M; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Crossland N; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Seyler-Schmidt M; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Staples H; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Silva-Ayala D; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, and Laboratory for Infectious Disease Research, University of Missouri School of Medicine, Columbia, MO 65211, USA., Laprise AM; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., St Denis L; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Grosz K; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., O'Connell A; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Gertje H; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Ripin T; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Decker C; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Mazur M; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Thurman C; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA., Espinoza M; International AIDS Vaccine Initiative, New York, NY 10004, USA., Morrow G; International AIDS Vaccine Initiative, New York, NY 10004, USA., Parks CL; International AIDS Vaccine Initiative, New York, NY 10004, USA., Cooper CL; International AIDS Vaccine Initiative, New York, NY 10004, USA.; Tonix Pharmaceuticals, Frederick, MD 21701, USA., Griffiths A; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, and Laboratory for Infectious Disease Research, University of Missouri School of Medicine, Columbia, MO 65211, USA. |
| Source: | Viruses [Viruses] 2025 Oct 14; Vol. 17 (10). Date of Electronic Publication: 2025 Oct 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41157643 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Storm+N%22">Storm N</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Lo+M%22">Lo M</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Crossland+N%22">Crossland N</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Seyler-Schmidt+M%22">Seyler-Schmidt M</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Staples+H%22">Staples H</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Silva-Ayala+D%22">Silva-Ayala D</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, and Laboratory for Infectious Disease Research, University of Missouri School of Medicine, Columbia, MO 65211, USA.<br /><searchLink fieldCode="AU" term="%22Laprise+AM%22">Laprise AM</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22St+Denis+L%22">St Denis L</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Grosz+K%22">Grosz K</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22O'Connell+A%22">O'Connell A</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Gertje+H%22">Gertje H</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Ripin+T%22">Ripin T</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Decker+C%22">Decker C</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Mazur+M%22">Mazur M</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Thurman+C%22">Thurman C</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Espinoza+M%22">Espinoza M</searchLink>; International AIDS Vaccine Initiative, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Morrow+G%22">Morrow G</searchLink>; International AIDS Vaccine Initiative, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Parks+CL%22">Parks CL</searchLink>; International AIDS Vaccine Initiative, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+CL%22">Cooper CL</searchLink>; International AIDS Vaccine Initiative, New York, NY 10004, USA.; Tonix Pharmaceuticals, Frederick, MD 21701, USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+A%22">Griffiths A</searchLink>; National Emerging Infectious Diseases Laboratories, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Virology, Immunology and Microbiology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA.; Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, and Laboratory for Infectious Disease Research, University of Missouri School of Medicine, Columbia, MO 65211, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101509722%22">Viruses</searchLink> [Viruses] 2025 Oct 14; Vol. 17 (10). <i>Date of Electronic Publication: </i>2025 Oct 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101509722 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1999-4915 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994915%22">19994915 </searchLink><i>NLM ISO Abbreviation: </i>Viruses <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/v17101373 Languages: – Code: eng Text: English Titles: – TitleFull: An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Storm N – PersonEntity: Name: NameFull: Lo M – PersonEntity: Name: NameFull: Crossland N – PersonEntity: Name: NameFull: Seyler-Schmidt M – PersonEntity: Name: NameFull: Staples H – PersonEntity: Name: NameFull: Silva-Ayala D – PersonEntity: Name: NameFull: Laprise AM – PersonEntity: Name: NameFull: St Denis L – PersonEntity: Name: NameFull: Grosz K – PersonEntity: Name: NameFull: O'Connell A – PersonEntity: Name: NameFull: Gertje H – PersonEntity: Name: NameFull: Ripin T – PersonEntity: Name: NameFull: Decker C – PersonEntity: Name: NameFull: Mazur M – PersonEntity: Name: NameFull: Thurman C – PersonEntity: Name: NameFull: Espinoza M – PersonEntity: Name: NameFull: Morrow G – PersonEntity: Name: NameFull: Parks CL – PersonEntity: Name: NameFull: Cooper CL – PersonEntity: Name: NameFull: Griffiths A IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 10 Text: 2025 Oct 14 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1999-4915 Numbering: – Type: volume Value: 17 – Type: issue Value: 10 Titles: – TitleFull: Viruses Type: main |
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