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Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population.

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Title: Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population.
Authors: Mercuri FA; ENA Respiratory, Melbourne, VIC, Australia.; School of Pharmacy and Medical Science and the Institute for Biomedicine and Glycomics, Griffith University, QLD, Australia., Zhuang A; School of Pharmacy and Medical Science and the Institute for Biomedicine and Glycomics, Griffith University, QLD, Australia.; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia., McQuilten HA; ENA Respiratory, Melbourne, VIC, Australia., Jarnicki A; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia., O'Donoghue R; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia., O'Brien C; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia., Ciccotosto GD; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia., Zhang P; Griffith Biostatistics Unit, Griffith Health, Griffith University Gold Coast Campus, QLD, Australia., Demaison C; ENA Respiratory, Melbourne, VIC, Australia., White S; ENA Respiratory, Melbourne, VIC, Australia., West NP; Griffith Biostatistics Unit, Griffith Health, Griffith University Gold Coast Campus, QLD, Australia., Tal-Singer R; ENA Respiratory, Melbourne, VIC, Australia.; F.A. Mercuri and A. Zhuang contributed equally., Anderson GP; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; F.A. Mercuri and A. Zhuang contributed equally.
Source: ERJ open research [ERJ Open Res] 2025 Oct 27; Vol. 11 (5). Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE
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  Data: Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population.
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  Data: <searchLink fieldCode="AU" term="%22Mercuri+FA%22">Mercuri FA</searchLink>; ENA Respiratory, Melbourne, VIC, Australia.; School of Pharmacy and Medical Science and the Institute for Biomedicine and Glycomics, Griffith University, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Zhuang+A%22">Zhuang A</searchLink>; School of Pharmacy and Medical Science and the Institute for Biomedicine and Glycomics, Griffith University, QLD, Australia.; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22McQuilten+HA%22">McQuilten HA</searchLink>; ENA Respiratory, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Jarnicki+A%22">Jarnicki A</searchLink>; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22O'Donoghue+R%22">O'Donoghue R</searchLink>; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22O'Brien+C%22">O'Brien C</searchLink>; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ciccotosto+GD%22">Ciccotosto GD</searchLink>; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Griffith Biostatistics Unit, Griffith Health, Griffith University Gold Coast Campus, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Demaison+C%22">Demaison C</searchLink>; ENA Respiratory, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22White+S%22">White S</searchLink>; ENA Respiratory, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22West+NP%22">West NP</searchLink>; Griffith Biostatistics Unit, Griffith Health, Griffith University Gold Coast Campus, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Tal-Singer+R%22">Tal-Singer R</searchLink>; ENA Respiratory, Melbourne, VIC, Australia.; F.A. Mercuri and A. Zhuang contributed equally.<br /><searchLink fieldCode="AU" term="%22Anderson+GP%22">Anderson GP</searchLink>; Deparment of Biochemistry and Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; Lung Health Research Centre, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia.; F.A. Mercuri and A. Zhuang contributed equally.
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  Data: <searchLink fieldCode="JN" term="%22101671641%22">ERJ open research</searchLink> [ERJ Open Res] 2025 Oct 27; Vol. 11 (5). <i>Date of Electronic Publication: </i>2025 Oct 27 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22European+Respiratory+Society%22">European Respiratory Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101671641 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2312-0541 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223120541%22">23120541 </searchLink><i>NLM ISO Abbreviation: </i>ERJ Open Res <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Oct 27
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