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Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels.

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Title: Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels.
Authors: Yao YD; Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Hospital of Traditional Chinese Medicine, No. 61 Dongmen Road, Guancheng District, Dongguan 523200, China., Li JM; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Zhu ZH; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Li QL; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Luo JF; Department of Basic Medicine, Department of Pharmacy, Key Laboratory on the Property & Effect of Chinese Medicine (Ethnic Medicine), Guizhou Genuine Herbs Center of Consistency of Utility, The Provincial Key Miao Medicine Laboratory of Guizhou, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China., Zhang MX; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Feng CL; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Deng HS; Community health service center of DAGANGTOWN, Nansha District, Guangzhou, No. 4 Lingshan Huancheng East Road, Dagang Town, Nansha District, Guangzhou 511458, China., Pi FC; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China., Huang SG; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16, Airport Road, Guangzhou 510405, China. Electronic address: huangshaogang@gzucm.edu.cn., Peng JH; Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Hospital of Traditional Chinese Medicine, No. 61 Dongmen Road, Guancheng District, Dongguan 523200, China. Electronic address: 925294293@qq.com., Xie Y; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China. Electronic address: leoxieying16@outlook.com., Zhou H; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China. Electronic address: gutcmzhs@hotmail.com.
Source: Pharmacological research [Pharmacol Res] 2025 Dec; Vol. 222, pp. 108009. Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Investigating the intercalation efficacy of sinomenine with diverse DNA fragments to understand its regulatory role in DNA methylation levels.
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  Data: <searchLink fieldCode="AU" term="%22Yao+YD%22">Yao YD</searchLink>; Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Hospital of Traditional Chinese Medicine, No. 61 Dongmen Road, Guancheng District, Dongguan 523200, China.<br /><searchLink fieldCode="AU" term="%22Li+JM%22">Li JM</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Zhu+ZH%22">Zhu ZH</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Li+QL%22">Li QL</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Luo+JF%22">Luo JF</searchLink>; Department of Basic Medicine, Department of Pharmacy, Key Laboratory on the Property & Effect of Chinese Medicine (Ethnic Medicine), Guizhou Genuine Herbs Center of Consistency of Utility, The Provincial Key Miao Medicine Laboratory of Guizhou, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.<br /><searchLink fieldCode="AU" term="%22Zhang+MX%22">Zhang MX</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Feng+CL%22">Feng CL</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Deng+HS%22">Deng HS</searchLink>; Community health service center of DAGANGTOWN, Nansha District, Guangzhou, No. 4 Lingshan Huancheng East Road, Dagang Town, Nansha District, Guangzhou 511458, China.<br /><searchLink fieldCode="AU" term="%22Pi+FC%22">Pi FC</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China.<br /><searchLink fieldCode="AU" term="%22Huang+SG%22">Huang SG</searchLink>; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16, Airport Road, Guangzhou 510405, China. Electronic address: huangshaogang@gzucm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Peng+JH%22">Peng JH</searchLink>; Dongguan Hospital of Guangzhou University of Chinese Medicine, Dongguan Hospital of Traditional Chinese Medicine, No. 61 Dongmen Road, Guancheng District, Dongguan 523200, China. Electronic address: 925294293@qq.com.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China. Electronic address: leoxieying16@outlook.com.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory (Hengqin Laboratory), and State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou 510006, China. Electronic address: gutcmzhs@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%228907422%22">Pharmacological research</searchLink> [Pharmacol Res] 2025 Dec; Vol. 222, pp. 108009. <i>Date of Electronic Publication: </i>2025 Oct 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8907422 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-1186 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210436618%22">10436618 </searchLink><i>NLM ISO Abbreviation: </i>Pharmacol Res <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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        Value: 10.1016/j.phrs.2025.108009
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      – Code: eng
        Text: English
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        StartPage: 108009
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            – D: 01
              M: 12
              Text: 2025 Dec
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