Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites.

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Title: Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites.
Authors: Ahmadi S; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Burlet NJ; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Benard-Valle M; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Guadarrama-Martínez A; Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México., Kerwin S; Department of Biological Sciences, University of Northern Colorado, Greeley, CO, USA., Cardoso IA; Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.; School of Biochemistry, Biomedical Sciences Building, University of Bristol, Bristol, UK., Marriott AE; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Edge RJ; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Crittenden E; Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Neri-Castro E; Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México., Fernandez-Quintero ML; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Nguyen GTT; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., O'Brien C; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Wouters Y; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Kalogeropoulos K; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Thumtecho S; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.; Division of Toxicology, Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand., Ebersole TW; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Dahl CH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Glegg-Sørensen EU; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Jansen T; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Boddum K; Sophion Bioscience, Ballerup, Denmark., Manousaki E; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Rivera-de-Torre E; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Morth JP; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark., Alagón A; Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México., Mackessy SP; Department of Biological Sciences, University of Northern Colorado, Greeley, CO, USA., Ainsworth S; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Menzies SK; Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, UK., Casewell NR; Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK., Jenkins TP; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. tpaje@dtu.dk., Ljungars A; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. aellj@dtu.dk., Laustsen AH; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. ahola@bio.dtu.dk.
Source: Nature [Nature] 2025 Nov; Vol. 647 (8090), pp. 716-725. Date of Electronic Publication: 2025 Oct 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.; School of Biochemistry, Biomedical Sciences Building, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Marriott+AE%22">Marriott AE</searchLink>; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Edge+RJ%22">Edge RJ</searchLink>; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Crittenden+E%22">Crittenden E</searchLink>; Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Neri-Castro+E%22">Neri-Castro E</searchLink>; Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México.<br /><searchLink fieldCode="AU" term="%22Fernandez-Quintero+ML%22">Fernandez-Quintero ML</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+GTT%22">Nguyen GTT</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22O'Brien+C%22">O'Brien C</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Wouters+Y%22">Wouters Y</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Kalogeropoulos+K%22">Kalogeropoulos K</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Thumtecho+S%22">Thumtecho S</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.; Division of Toxicology, Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Ebersole+TW%22">Ebersole TW</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Dahl+CH%22">Dahl CH</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Glegg-Sørensen+EU%22">Glegg-Sørensen EU</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Jansen+T%22">Jansen T</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Boddum+K%22">Boddum K</searchLink>; Sophion Bioscience, Ballerup, Denmark.<br /><searchLink fieldCode="AU" term="%22Manousaki+E%22">Manousaki E</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Rivera-de-Torre+E%22">Rivera-de-Torre E</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Morth+JP%22">Morth JP</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Alagón+A%22">Alagón A</searchLink>; Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, México.<br /><searchLink fieldCode="AU" term="%22Mackessy+SP%22">Mackessy SP</searchLink>; Department of Biological Sciences, University of Northern Colorado, Greeley, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ainsworth+S%22">Ainsworth S</searchLink>; Department of Infection Biology and Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Menzies+SK%22">Menzies SK</searchLink>; Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.<br /><searchLink fieldCode="AU" term="%22Casewell+NR%22">Casewell NR</searchLink>; Centre for Snakebite Research and Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Jenkins+TP%22">Jenkins TP</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. tpaje@dtu.dk.<br /><searchLink fieldCode="AU" term="%22Ljungars+A%22">Ljungars A</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. aellj@dtu.dk.<br /><searchLink fieldCode="AU" term="%22Laustsen+AH%22">Laustsen AH</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark. ahola@bio.dtu.dk.
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