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3D printed hydroxyurea for pediatric use: toward personalized formulations and reduced exposure risk.

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Title: 3D printed hydroxyurea for pediatric use: toward personalized formulations and reduced exposure risk.
Authors: Laverdière J; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: jean.laverdiere@umontreal.ca., Bendicho-Lavilla C; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7, 15702 Santiago de Compostela, Spain; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK. Electronic address: carlos.bendicho@fabrx.co.uk., Mahrouche L; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: louiza.mahrouche@umontreal.ca., Friciu M; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: mihaela.friciu@umontreal.ca., Pastore Y; Pediatric Department, Hematology Section, CHU Sainte-Justine, 3175 Chem. de la Côte-Sainte-Catherine, Montréal H3T 1C5, Canada. Electronic address: yves.pastore.med@ssss.gouv.qc.ca., Leclair G; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: gregoire.leclair@umontreal.ca., Basit AW; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK. Electronic address: a.basit@ucl.ac.uk., Goyanes A; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7, 15702 Santiago de Compostela, Spain; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK; Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma (GI-1645), Facultad de Farmacia, Instituto de Materiales (iMATUS) and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela 15782 Santiago de Compostela, Spain. Electronic address: a.goyanes@fabrx.co.uk., Roullin VG; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: vg.roullin@umontreal.ca.
Source: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126326. Date of Electronic Publication: 2025 Oct 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Laverdière+J%22">Laverdière J</searchLink>; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: jean.laverdiere@umontreal.ca.<br /><searchLink fieldCode="AU" term="%22Bendicho-Lavilla+C%22">Bendicho-Lavilla C</searchLink>; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7, 15702 Santiago de Compostela, Spain; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK. Electronic address: carlos.bendicho@fabrx.co.uk.<br /><searchLink fieldCode="AU" term="%22Mahrouche+L%22">Mahrouche L</searchLink>; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: louiza.mahrouche@umontreal.ca.<br /><searchLink fieldCode="AU" term="%22Friciu+M%22">Friciu M</searchLink>; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: mihaela.friciu@umontreal.ca.<br /><searchLink fieldCode="AU" term="%22Pastore+Y%22">Pastore Y</searchLink>; Pediatric Department, Hematology Section, CHU Sainte-Justine, 3175 Chem. de la Côte-Sainte-Catherine, Montréal H3T 1C5, Canada. Electronic address: yves.pastore.med@ssss.gouv.qc.ca.<br /><searchLink fieldCode="AU" term="%22Leclair+G%22">Leclair G</searchLink>; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: gregoire.leclair@umontreal.ca.<br /><searchLink fieldCode="AU" term="%22Basit+AW%22">Basit AW</searchLink>; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK. Electronic address: a.basit@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Goyanes+A%22">Goyanes A</searchLink>; FABRX Artificial Intelligence, Calle Enrique Vidal Abascal 7, 15702 Santiago de Compostela, Spain; FABRX Ltd., Henwood House, Henwood, Ashford, Kent TN24 8DH, UK; Department of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK; Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, I+D Farma (GI-1645), Facultad de Farmacia, Instituto de Materiales (iMATUS) and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela 15782 Santiago de Compostela, Spain. Electronic address: a.goyanes@fabrx.co.uk.<br /><searchLink fieldCode="AU" term="%22Roullin+VG%22">Roullin VG</searchLink>; Platform of Biopharmacy, Université de Montréal, 2940 Chem. de Polytechnique, Montréal H3T 1J4, Canada. Electronic address: vg.roullin@umontreal.ca.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126326. <i>Date of Electronic Publication: </i>2025 Oct 28.
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              Text: 2025 Dec 25
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