Efficacy of the GLP-1 receptor agonist, semaglutide, in abstinence from illicit and nonprescribed opioids in an outpatient population with OUD: a randomized, double-blind, placebo-controlled clinical trial protocol.
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| Title: | Efficacy of the GLP-1 receptor agonist, semaglutide, in abstinence from illicit and nonprescribed opioids in an outpatient population with OUD: a randomized, double-blind, placebo-controlled clinical trial protocol. |
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| Authors: | Freet CS; Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, USA., Shuler K; Department of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Kawasaki S; Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, USA.; Pennsylvania Psychiatric Institute, Penn State Health, Harrisburg, PA, USA.; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA., Weintraub E; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA., Greenblatt A; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA., Kladney M; Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.; Bellevue Hospital Center, New York, NY, USA., Nunes E; Division of Substance Use Disorders, Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA., Foster KL; National Institute on Drug Abuse, Bethesda, MD, USA., Kong L; Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA., Raja-Khan N; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA., Cleveland HH; Department of Human Development and Family Studies, Pennsylvania State University, University Park, PA, USA., Grigson PS; Department of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Bunce SC; Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA, USA., Brick TR; Department of Human Development and Family Studies, Pennsylvania State University, University Park, PA, USA.; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA, USA., Nyland JE; Department of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, 500 University Drive, Hershey, PA, 17033, USA. jnyland@pennstatehealth.psu.edu. |
| Source: | Addiction science & clinical practice [Addict Sci Clin Pract] 2025 Oct 30; Vol. 20 (1), pp. 89. Date of Electronic Publication: 2025 Oct 30. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101316917 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-0640 (Electronic) Linking ISSN: 19400632 NLM ISO Abbreviation: Addict Sci Clin Pract Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1940-0640 |
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| DOI: | 10.1186/s13722-025-00618-2 |
