Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine.

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Title: Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine.
Authors: Owumi S; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria. zicri@hotmail.com., Emmanuel PD; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria., Chimezie J; Department of Physiology, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria., Joel FO; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria., Idris B; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria., Babalola JO; Neuroanatomy Research Laboratories, Department of Anatomy, University of Ibadan, Ibadan, 200005, Oyo State, Nigeria., Owoeye O; Nutrition and Industrial Biochemistry Research Laboratories, Department of Biochemistry, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Feb; Vol. 399 (4), pp. 5319-5335. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
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  Data: Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine.
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  Data: <searchLink fieldCode="AU" term="%22Owumi+S%22">Owumi S</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria. zicri@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Emmanuel+PD%22">Emmanuel PD</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Chimezie+J%22">Chimezie J</searchLink>; Department of Physiology, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Joel+FO%22">Joel FO</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Idris+B%22">Idris B</searchLink>; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Babalola+JO%22">Babalola JO</searchLink>; Neuroanatomy Research Laboratories, Department of Anatomy, University of Ibadan, Ibadan, 200005, Oyo State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Owoeye+O%22">Owoeye O</searchLink>; Nutrition and Industrial Biochemistry Research Laboratories, Department of Biochemistry, University of Ibadan, 200005, Ibadan, Oyo State, Nigeria.
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        Value: 10.1007/s00210-025-04723-6
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      – TitleFull: Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine.
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              Text: 2026 Feb
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