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Excessive compression induces cartilage endplate degeneration via the Piezo1/NAT10/mTOR signaling axis.

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Bibliographic Details
Title: Excessive compression induces cartilage endplate degeneration via the Piezo1/NAT10/mTOR signaling axis.
Authors: Sun H; Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China. Electronic address: 976957465@qq.com., Wu Z; Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China. Electronic address: 2316674820@qq.com., Zhang Y; Spine Research Center of Wannan Medical College, No.22 Wenchang West Road, Wuhu, Anhui 241001, China. Electronic address: lakerszy@126.com., Liu C; Spine Research Center of Wannan Medical College, No.22 Wenchang West Road, Wuhu, Anhui 241001, China. Electronic address: 18715536572@163.com., Gao D; Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China. Electronic address: 895164183@qq.com., Zhao Q; Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China. Electronic address: quanlai1986@126.com., Xiao L; Department of Spine Surgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China; Key Laboratory of Non-Coding RNA Transformation Research of Anhui Higher Education Institution, No. 2 Zheshan West Road, Wuhu, Anhui 241001, China. Electronic address: xlllan2012@126.com.
Source: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2026 Apr; Vol. 34 (4), pp. 550-562. Date of Electronic Publication: 2025 Oct 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: W.B. Saunders For The Osteoarthritis Research Society Country of Publication: England NLM ID: 9305697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-9653 (Electronic) Linking ISSN: 10634584 NLM ISO Abbreviation: Osteoarthritis Cartilage Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-9653
DOI:10.1016/j.joca.2025.10.014