Microfracture with or without collagen scaffold insertion for adults with chondral or osteochondral defects of the knee: the SISMIC RCT and its challenges during and after the COVID-19 pandemic.
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| Title: | Microfracture with or without collagen scaffold insertion for adults with chondral or osteochondral defects of the knee: the SISMIC RCT and its challenges during and after the COVID-19 pandemic. |
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| Authors: | Whitehouse MR; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK.; The NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.; Avon Orthopaedic Centre, Neuroscience and Musculoskeletal Division, North Bristol NHS Trust, Southmead Hospital, Bristol, UK., Howells N; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK.; Avon Orthopaedic Centre, Neuroscience and Musculoskeletal Division, North Bristol NHS Trust, Southmead Hospital, Bristol, UK., Dabner L; Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK., Thirard R; Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK., Culliford L; Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK., Marques E; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK., Baji P; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK., Judge A; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK.; The NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK., Blom AW; The NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.; Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK., Burston A; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK., Jameson C; Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK., Rogers CA; Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, UK. |
| Source: | Health technology assessment (Winchester, England) [Health Technol Assess] 2025 Oct 29, pp. 1-25. Date of Electronic Publication: 2025 Oct 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: NIHR Journals Library Country of Publication: England NLM ID: 9706284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-4924 (Electronic) Linking ISSN: 13665278 NLM ISO Abbreviation: Health Technol Assess Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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