A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity.

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Title: A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity.
Authors: Etna MP; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy., Fuoco C; Department of Biology, University of Rome Tor Vergata, Rome, Italy., Severa M; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy., Ricci D; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy., Sinigaglia A; Department of Molecular Medicine, University of Padova, Padua, Italy., Lucca C; Department of Molecular Medicine, University of Padova, Padua, Italy., Cairo G; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy., Bottazzi B; Department of Inflammation and Immunology, Humanitas Clinical and Research Centre - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy., Garlanda C; Department of Inflammation and Immunology, Humanitas Clinical and Research Centre - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Palamara AT; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy., Barzon L; Department of Molecular Medicine, University of Padova, Padua, Italy., Gargioli C; Department of Biology, University of Rome Tor Vergata, Rome, Italy., Coccia EM; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.
Source: Frontiers in immunology [Front Immunol] 2025 Oct 10; Vol. 16, pp. 1651095. Date of Electronic Publication: 2025 Oct 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity.
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  Data: <searchLink fieldCode="AU" term="%22Etna+MP%22">Etna MP</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fuoco+C%22">Fuoco C</searchLink>; Department of Biology, University of Rome Tor Vergata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Severa+M%22">Severa M</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ricci+D%22">Ricci D</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Sinigaglia+A%22">Sinigaglia A</searchLink>; Department of Molecular Medicine, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Lucca+C%22">Lucca C</searchLink>; Department of Molecular Medicine, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Cairo+G%22">Cairo G</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bottazzi+B%22">Bottazzi B</searchLink>; Department of Inflammation and Immunology, Humanitas Clinical and Research Centre - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Garlanda+C%22">Garlanda C</searchLink>; Department of Inflammation and Immunology, Humanitas Clinical and Research Centre - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Palamara+AT%22">Palamara AT</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Barzon+L%22">Barzon L</searchLink>; Department of Molecular Medicine, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Gargioli+C%22">Gargioli C</searchLink>; Department of Biology, University of Rome Tor Vergata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Coccia+EM%22">Coccia EM</searchLink>; Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Oct 10; Vol. 16, pp. 1651095. <i>Date of Electronic Publication: </i>2025 Oct 10 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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