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GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy.

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Title: GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy.
Authors: Budak M; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States., Moraes MP; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States., Greenstein T; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States.; Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA, United States., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Borish HJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Chishti HB; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Kracinovsky K; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Rodgers M; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Tomko J; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Lin PL; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, United States., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States., Aldridge BB; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States.; Department of Biomedical Engineering, Tufts University School of Engineering, Medford, MA, United States., Kirschner D; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Oct 17; Vol. 16, pp. 1639673. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Budak+M%22">Budak M</searchLink>; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.<br /><searchLink fieldCode="AU" term="%22Moraes+MP%22">Moraes MP</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Greenstein+T%22">Greenstein T</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States.; Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Maiello+P%22">Maiello P</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Borish+HJ%22">Borish HJ</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Chishti+HB%22">Chishti HB</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Kracinovsky+K%22">Kracinovsky K</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Rodgers+M%22">Rodgers M</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Tomko+J%22">Tomko J</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Lin+PL%22">Lin PL</searchLink>; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Flynn+JL%22">Flynn JL</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Aldridge+BB%22">Aldridge BB</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States.; Department of Biomedical Engineering, Tufts University School of Engineering, Medford, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kirschner+D%22">Kirschner D</searchLink>; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2025 Oct 17; Vol. 16, pp. 1639673. <i>Date of Electronic Publication: </i>2025 Oct 17 (<i>Print Publication: </i>2025).
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