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Pathological response calculation assessment remains accurate with reduced tumor bed examination after neoadjuvant immunotherapy in clinically detectable stage III melanoma.

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Title: Pathological response calculation assessment remains accurate with reduced tumor bed examination after neoadjuvant immunotherapy in clinically detectable stage III melanoma.
Authors: Rawson RV; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; NSW Health Pathology, Sydney, Australia., Maher NG; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Menzies AM; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., Lo SN; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia., Mesbah Ardakani N; Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Perth, Australia., Jackett LA; Peter MacCallum Cancer Centre, Melbourne, Australia., Vergara IA; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia., Pennington TE; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., Shannon KF; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., Ch'ng S; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., Gonzalez M; Melanoma Institute Australia, The University of Sydney, Sydney, Australia., Burton EM; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA., Lucas MW; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Reijers ILM; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Rozeman EA; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Gyorki DE; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Sandhu S; Peter MacCallum Cancer Centre, Melbourne, Australia., Carlino MS; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Westmead Hospital, Sydney, Australia; Blacktown Hospital, Sydney, Australia., Howle J; Westmead Hospital, Sydney, Australia., Khattak M; Fiona Stanley Hospital, Edith Cowan University, Perth, Australia., Van der Westhuizen A; Lake Macquarie Oncology, Lake Macquarie Private Hospital, The Department of Medicine, University of Newcastle, Newcastle, Australia., Andrews MC; Department of Medical Oncology, Alfred Health, Melbourne, Australia; Department of Medicine, School of Translational Medicine, Monash University, Melbourne, Australia., Atkinson V; Princess Alexandra Hospital, University of Queensland, Brisbane, Australia., van Akkooi ACJ; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia., Spillane AJ; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., Saw RPM; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia., van de Wiel BA; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Blank CU; The Netherlands Cancer Institute, Amsterdam, The Netherlands., Long GV; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia., Tetzlaff MT; Departments of Pathology and Dermatology, Dermatopathology and Oral Pathology Unit, University of California, San Francisco, USA. Electronic address: michael.tetzlaff@ucsf.edu., Scolyer RA; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; NSW Health Pathology, Sydney, Australia; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address: Richard.Scolyer@health.nsw.gov.au.
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2026 Feb; Vol. 37 (2), pp. 206-216. Date of Electronic Publication: 2025 Nov 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pathological response calculation assessment remains accurate with reduced tumor bed examination after neoadjuvant immunotherapy in clinically detectable stage III melanoma.
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  Data: <searchLink fieldCode="AU" term="%22Rawson+RV%22">Rawson RV</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; NSW Health Pathology, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Maher+NG%22">Maher NG</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Menzies+AM%22">Menzies AM</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Lo+SN%22">Lo SN</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Mesbah+Ardakani+N%22">Mesbah Ardakani N</searchLink>; Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Jackett+LA%22">Jackett LA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Vergara+IA%22">Vergara IA</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Pennington+TE%22">Pennington TE</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Shannon+KF%22">Shannon KF</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Ch'ng+S%22">Ch'ng S</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Gonzalez+M%22">Gonzalez M</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Burton+EM%22">Burton EM</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+MW%22">Lucas MW</searchLink>; The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Reijers+ILM%22">Reijers ILM</searchLink>; The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rozeman+EA%22">Rozeman EA</searchLink>; The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gyorki+DE%22">Gyorki DE</searchLink>; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Sandhu+S%22">Sandhu S</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Carlino+MS%22">Carlino MS</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Westmead Hospital, Sydney, Australia; Blacktown Hospital, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Howle+J%22">Howle J</searchLink>; Westmead Hospital, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Khattak+M%22">Khattak M</searchLink>; Fiona Stanley Hospital, Edith Cowan University, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Van+der+Westhuizen+A%22">Van der Westhuizen A</searchLink>; Lake Macquarie Oncology, Lake Macquarie Private Hospital, The Department of Medicine, University of Newcastle, Newcastle, Australia.<br /><searchLink fieldCode="AU" term="%22Andrews+MC%22">Andrews MC</searchLink>; Department of Medical Oncology, Alfred Health, Melbourne, Australia; Department of Medicine, School of Translational Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Atkinson+V%22">Atkinson V</searchLink>; Princess Alexandra Hospital, University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22van+Akkooi+ACJ%22">van Akkooi ACJ</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Spillane+AJ%22">Spillane AJ</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Saw+RPM%22">Saw RPM</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22van+de+Wiel+BA%22">van de Wiel BA</searchLink>; The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Blank+CU%22">Blank CU</searchLink>; The Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Long+GV%22">Long GV</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal North Shore, Sydney, Australia; The Mater Hospital, Wollstonecraft, Sydney, Australia; Charles Perkins Centre, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Tetzlaff+MT%22">Tetzlaff MT</searchLink>; Departments of Pathology and Dermatology, Dermatopathology and Oral Pathology Unit, University of California, San Francisco, USA. Electronic address: michael.tetzlaff@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Scolyer+RA%22">Scolyer RA</searchLink>; Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia; Royal Prince Alfred Hospital, Sydney, Australia; NSW Health Pathology, Sydney, Australia; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA. Electronic address: Richard.Scolyer@health.nsw.gov.au.
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