Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugs.
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| Title: | Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugs. |
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| Authors: | Sadagopan A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Division of Medical Sciences, Harvard Medical School, Boston, MA, USA., Carson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Zamurs EJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Garaffo N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Division of Medical Sciences, Harvard Medical School, Boston, MA, USA., Chang HJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schreiber SL; Broad Institute of MIT and Harvard, Cambridge, MA, USA. stuart_schreiber@harvard.edu.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA. stuart_schreiber@harvard.edu., Meyerson M; Broad Institute of MIT and Harvard, Cambridge, MA, USA. matthew_meyerson@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. matthew_meyerson@dfci.harvard.edu., Gibson WJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA. william_gibson@dfci.harvard.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. william_gibson@dfci.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. william_gibson@dfci.harvard.edu. |
| Source: | Nature chemical biology [Nat Chem Biol] 2026 May; Vol. 22 (5), pp. 783-792. Date of Electronic Publication: 2025 Nov 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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