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Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.

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Title: Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.
Authors: Simonson AW; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: awsimonson@pitt.edu., Chao MC; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: mchao@hsph.harvard.edu., Hood LE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: leh107@pitt.edu., Donlan RA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: rad183@pitt.edu., Hopkins F; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: fhopkins@hsph.harvard.edu., Chase MR; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: mrchase@hsph.harvard.edu., Vickers AJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: avickers@hsph.harvard.edu., Callendrello A; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: acallend@hsph.harvard.edu., Klein E; Division of Animal Laboratory Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: eklein@pitt.edu., Borish H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: hjb25@pitt.edu., Malin M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: mam1523@pitt.edu., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: pam113@pitt.edu., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: scangaca@pitt.edu., Lin PL; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, USA. Electronic address: philana.lin@chp.edu., Fortune SM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: sfortune@hsph.harvard.edu., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: joanne@pitt.edu.
Source: Mucosal immunology [Mucosal Immunol] 2026 Feb; Vol. 19 (1), pp. 1538-1549. Date of Electronic Publication: 2025 Nov 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE
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  Data: Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages.
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  Data: <searchLink fieldCode="AU" term="%22Simonson+AW%22">Simonson AW</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: awsimonson@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Chao+MC%22">Chao MC</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: mchao@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Hood+LE%22">Hood LE</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: leh107@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Donlan+RA%22">Donlan RA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: rad183@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Hopkins+F%22">Hopkins F</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: fhopkins@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Chase+MR%22">Chase MR</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: mrchase@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Vickers+AJ%22">Vickers AJ</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: avickers@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Callendrello+A%22">Callendrello A</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: acallend@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Klein+E%22">Klein E</searchLink>; Division of Animal Laboratory Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: eklein@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Borish+H%22">Borish H</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: hjb25@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Malin+M%22">Malin M</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: mam1523@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Maiello+P%22">Maiello P</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: pam113@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Scanga+CA%22">Scanga CA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: scangaca@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Lin+PL%22">Lin PL</searchLink>; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA, USA. Electronic address: philana.lin@chp.edu.<br /><searchLink fieldCode="AU" term="%22Fortune+SM%22">Fortune SM</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: sfortune@hsph.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Flynn+JL%22">Flynn JL</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: joanne@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101299742%22">Mucosal immunology</searchLink> [Mucosal Immunol] 2026 Feb; Vol. 19 (1), pp. 1538-1549. <i>Date of Electronic Publication: </i>2025 Nov 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101299742 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1935-3456 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219330219%22">19330219 </searchLink><i>NLM ISO Abbreviation: </i>Mucosal Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.mucimm.2025.10.010
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