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Unexpected effects of antibiotics on microbiota-mediated drug metabolism in a fistulated dog model.

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Title: Unexpected effects of antibiotics on microbiota-mediated drug metabolism in a fistulated dog model.
Authors: Sousa T; UCL School of Pharmacy, University College London, London WC1N 1AX, UK., Yeung C; UCL School of Pharmacy, University College London, London WC1N 1AX, UK., De Monsales CB; UCL School of Pharmacy, University College London, London WC1N 1AX, UK., Sangfuang N; UCL School of Pharmacy, University College London, London WC1N 1AX, UK., Borde A; New Modalities Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Gothenburg, Sweden., Abrahamsson B; Oral Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Gothenburg, Sweden., Basit AW; UCL School of Pharmacy, University College London, London WC1N 1AX, UK. Electronic address: a.basit@ucl.ac.uk.
Source: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2026 Jan 01; Vol. 216, pp. 107360. Date of Electronic Publication: 2025 Nov 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sousa+T%22">Sousa T</searchLink>; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.<br /><searchLink fieldCode="AU" term="%22Yeung+C%22">Yeung C</searchLink>; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.<br /><searchLink fieldCode="AU" term="%22De+Monsales+CB%22">De Monsales CB</searchLink>; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.<br /><searchLink fieldCode="AU" term="%22Sangfuang+N%22">Sangfuang N</searchLink>; UCL School of Pharmacy, University College London, London WC1N 1AX, UK.<br /><searchLink fieldCode="AU" term="%22Borde+A%22">Borde A</searchLink>; New Modalities Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Abrahamsson+B%22">Abrahamsson B</searchLink>; Oral Product Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Basit+AW%22">Basit AW</searchLink>; UCL School of Pharmacy, University College London, London WC1N 1AX, UK. Electronic address: a.basit@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229317982%22">European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences</searchLink> [Eur J Pharm Sci] 2026 Jan 01; Vol. 216, pp. 107360. <i>Date of Electronic Publication: </i>2025 Nov 02.
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