Febuxostat attenuates cyclophosphamide-induced ovarian toxicity; role of TLR4/NFκB/NLRP3 signaling pathway in female wistar albino rats.

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Title: Febuxostat attenuates cyclophosphamide-induced ovarian toxicity; role of TLR4/NFκB/NLRP3 signaling pathway in female wistar albino rats.
Authors: Abdelzaher WY; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt.; Faculty of Nursing, Lotus University, Minia, Egypt., Hassan M; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt., Abdel-Aziz AM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt., Abd Elghfar MHM; Department of Obstetrics & Gynecology, Faculty of Medicine, Minia University, Minia, Egypt., Reda S; Department of Obstetrics & Gynecology, Faculty of Medicine, Minia University, Minia, Egypt., Saleh RK; Department of Pathology, Faculty of Medicine, Minia University, Minia, Egypt., Atta M; Department of Anatomy, Faculty of Medicine, Minia University, Minia, Egypt., Mohamed AA; Department of Medical Physiology, Faculty of Medicine, Minia University, Minia, Egypt., Elsayed SH; Department of Medical Biochemistry, Faculty of Medicine, Minia University, Minia, Egypt., Taghian AS; Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Minia University, Minia, Egypt., Khalaf HM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia, Egypt.
Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2025 Dec; Vol. 47 (6), pp. 817-825. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-2513
DOI:10.1080/08923973.2025.2583496