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Benchmarking porcine pancreatic ductal organoids for drug screening applications.

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Title: Benchmarking porcine pancreatic ductal organoids for drug screening applications.
Authors: Karampelias C; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Yang K; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Farkas FJ; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Sterr M; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Molina van Den Bosch M; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany., Renner S; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany., Fuß J; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität Kiel, Kiel, Germany., von Toerne C; Metabolomics and Proteomics Core, Helmholtz Center Munich, German Research Center for Environmental Health, D-80939, Munich, Germany., Franzenburg S; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität Kiel, Kiel, Germany., Kin T; Clinical Islet Laboratory, University of Alberta Hospital, Edmonton, AB, Canada., Wolf E; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany., Kemter E; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany., Lickert H; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; German Center for Diabetes Research (DZD), Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; School of Medicine and Health, Technische Universität München, Munich, Germany. heiko.lickert@helmholtz-munich.de.
Source: EMBO molecular medicine [EMBO Mol Med] 2025 Dec; Vol. 17 (12), pp. 3657-3688. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Benchmarking porcine pancreatic ductal organoids for drug screening applications.
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  Data: <searchLink fieldCode="AU" term="%22Karampelias+C%22">Karampelias C</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Farkas+FJ%22">Farkas FJ</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sterr+M%22">Sterr M</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Molina+van+Den+Bosch+M%22">Molina van Den Bosch M</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; School of Medicine and Health, Technische Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Renner+S%22">Renner S</searchLink>; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fuß+J%22">Fuß J</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22von+Toerne+C%22">von Toerne C</searchLink>; Metabolomics and Proteomics Core, Helmholtz Center Munich, German Research Center for Environmental Health, D-80939, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Franzenburg+S%22">Franzenburg S</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kin+T%22">Kin T</searchLink>; Clinical Islet Laboratory, University of Alberta Hospital, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Wolf+E%22">Wolf E</searchLink>; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kemter+E%22">Kemter E</searchLink>; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Gene Center and Center for Innovative Medical Models (CiMM), LMU Munich, Munich, Germany.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lickert+H%22">Lickert H</searchLink>; Institute of Diabetes and Regeneration Research, Helmholtz Munich, Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; German Center for Diabetes Research (DZD), Neuherberg, Germany. heiko.lickert@helmholtz-munich.de.; School of Medicine and Health, Technische Universität München, Munich, Germany. heiko.lickert@helmholtz-munich.de.
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              Text: 2025 Dec
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