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The cost of drug repurposing: parallel economic evaluation of mirtazapine for severe breathlessness in the multinational BETTER-B trial.

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Title: The cost of drug repurposing: parallel economic evaluation of mirtazapine for severe breathlessness in the multinational BETTER-B trial.
Authors: May P; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK. peter.d.may@kcl.ac.uk.; School of Medicine, Trinity College Dublin, Dublin, Ireland. peter.d.may@kcl.ac.uk., Normand C; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; School of Medicine, Trinity College Dublin, Dublin, Ireland., Oluyase AO; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK., Smith S; School of Medicine, Trinity College Dublin, Dublin, Ireland., Brown ST; Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research (LICTR), University of Leeds, Leeds, UK., Maddocks M; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK., Costantini M; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK., Bajwah S; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; King's College Hospital NHS Foundation Trust, Bessemer Road, London, UK., Kahnert K; Department of Palliative Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; MediCenter Germering, Germering, Germany., Simon ST; Department of Palliative Medicine and Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany., Ryan K; University College Dublin and Mater Misericordiae University Hospital Dublin, Dublin, Ireland., Currow DC; Flinders Ageing Alliance, Flinders University, South Australia, Australia., Johnson MJ; Wolfson Palliative Care Research Centre, Hull York Medical School, The University of Hull, Hull, UK., Hart SP; Respiratory Research Group, Hull York Medical School, University of Hull, Hull, UK., Krajnik M; Department of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland., Tanzi S; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Bolton CE; NIHR Nottingham Biomedical Research Centre, Translational Medical Sciences, School of Medicine, The University of Nottingham, Nottingham, UK., Janowiak P; Division of Pulmonology, Medical University of Gdańsk, Gdańsk, Poland., Turola E; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Jolley CJ; King's College Hospital NHS Foundation Trust, Bessemer Road, London, UK.; Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, King's College London, London, UK., Mather H; Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research (LICTR), University of Leeds, Leeds, UK., Murden G; Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research (LICTR), University of Leeds, Leeds, UK., Ghirotto L; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Farsides B; Brighton and Sussex Medical School, University of Sussex, Brighton, BN1 9PX, UK., Brown JM; Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research (LICTR), University of Leeds, Leeds, UK., Higginson IJ; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; King's College Hospital NHS Foundation Trust, Bessemer Road, London, UK.
Corporate Authors: BETTER-B consortium
Source: BMC health services research [BMC Health Serv Res] 2025 Nov 04; Vol. 25 (1), pp. 1442. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088677 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6963 (Electronic) Linking ISSN: 14726963 NLM ISO Abbreviation: BMC Health Serv Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The cost of drug repurposing: parallel economic evaluation of mirtazapine for severe breathlessness in the multinational BETTER-B trial.
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  Data: <searchLink fieldCode="AU" term="%22May+P%22">May P</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK. peter.d.may@kcl.ac.uk.; School of Medicine, Trinity College Dublin, Dublin, Ireland. peter.d.may@kcl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Normand+C%22">Normand C</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; School of Medicine, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Oluyase+AO%22">Oluyase AO</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.<br /><searchLink fieldCode="AU" term="%22Smith+S%22">Smith S</searchLink>; School of Medicine, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Brown+ST%22">Brown ST</searchLink>; Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research (LICTR), University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Maddocks+M%22">Maddocks M</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.<br /><searchLink fieldCode="AU" term="%22Costantini+M%22">Costantini M</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.<br /><searchLink fieldCode="AU" term="%22Bajwah+S%22">Bajwah S</searchLink>; Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; King's College Hospital NHS Foundation Trust, Bessemer Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Kahnert+K%22">Kahnert K</searchLink>; Department of Palliative Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; MediCenter Germering, Germering, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+ST%22">Simon ST</searchLink>; Department of Palliative Medicine and Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ryan+K%22">Ryan K</searchLink>; University College Dublin and Mater Misericordiae University Hospital Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Currow+DC%22">Currow DC</searchLink>; Flinders Ageing Alliance, Flinders University, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Johnson+MJ%22">Johnson MJ</searchLink>; Wolfson Palliative Care Research Centre, Hull York Medical School, The University of Hull, Hull, UK.<br /><searchLink fieldCode="AU" term="%22Hart+SP%22">Hart SP</searchLink>; Respiratory Research Group, Hull York Medical School, University of Hull, Hull, UK.<br /><searchLink fieldCode="AU" term="%22Krajnik+M%22">Krajnik M</searchLink>; Department of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Tanzi+S%22">Tanzi S</searchLink>; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Bolton+CE%22">Bolton CE</searchLink>; NIHR Nottingham Biomedical Research Centre, Translational Medical Sciences, School of Medicine, The University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Janowiak+P%22">Janowiak P</searchLink>; Division of Pulmonology, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Turola+E%22">Turola E</searchLink>; Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Jolley+CJ%22">Jolley CJ</searchLink>; 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Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, Bessemer Road, London, SE5 9PJ, UK.; King's College Hospital NHS Foundation Trust, Bessemer Road, London, UK.
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