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A novel SPECT-CT imaging platform for quantifying in vivo lung cytokine signals in COPD.

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Title: A novel SPECT-CT imaging platform for quantifying in vivo lung cytokine signals in COPD.
Authors: Welham B; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Bennett M; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Ostridge K; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology R&D BioPharmaceuticals, Astrazeneca, Gothenburg, Sweden., Guy M; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Zvavamwe C; Radiopharmacy Department, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Chilcott A; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Johns S; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Sundram F; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Spalluto CM; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Shaw E; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Harden S; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Department of Radiology, University Hospital Southampton, Southampton, UK., Alzetani A; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Lee P; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK., Lawson M; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Lackie P; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Michopoulou S; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Henley D; Radiopharmacy Department, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK., Kong A; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Fazleen A; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Cellura D; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., McCrae C; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, USA., Platt A; Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Belvisi MG; Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; National Heart and Lung Institute, Imperial College, London, UK., Staples KJ; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Wilkinson T; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Source: ERJ open research [ERJ Open Res] 2025 Nov 03; Vol. 11 (6). Date of Electronic Publication: 2025 Nov 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE
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  Data: A novel SPECT-CT imaging platform for quantifying in vivo lung cytokine signals in COPD.
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  Data: <searchLink fieldCode="AU" term="%22Welham+B%22">Welham B</searchLink>; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Bennett+M%22">Bennett M</searchLink>; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Ostridge+K%22">Ostridge K</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology R&D BioPharmaceuticals, Astrazeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Guy+M%22">Guy M</searchLink>; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Zvavamwe+C%22">Zvavamwe C</searchLink>; Radiopharmacy Department, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Chilcott+A%22">Chilcott A</searchLink>; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Johns+S%22">Johns S</searchLink>; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Sundram+F%22">Sundram F</searchLink>; Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Spalluto+CM%22">Spalluto CM</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Shaw+E%22">Shaw E</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Harden+S%22">Harden S</searchLink>; 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Nuclear Medicine, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Henley+D%22">Henley D</searchLink>; Radiopharmacy Department, Nuclear Medicine Physics and Radiopharmacy, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Kong+A%22">Kong A</searchLink>; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Fazleen+A%22">Fazleen A</searchLink>; Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Cellura+D%22">Cellura D</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22McCrae+C%22">McCrae C</searchLink>; 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Southampton NIHR Respiratory Biomedical Research Centre, University Hospital Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
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