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Which Analgesic Should We Use to Relieve Pain After Knee or Hip Arthroplasty? A Systematic Review and Network Meta-analysis of RCTs.

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Title: Which Analgesic Should We Use to Relieve Pain After Knee or Hip Arthroplasty? A Systematic Review and Network Meta-analysis of RCTs.
Authors: He H; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China., Li C; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China., Wen Z; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China., Zhang W; Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK.; Pain Centre Versus Arthritis, Nottingham, UK., Doherty M; Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK.; Pain Centre Versus Arthritis, Nottingham, UK., Zhang Y; Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Xie J; Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Wang Y; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China., Xie D; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China., Wei J; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, PR China.; FuRong Laboratory, Changsha, Hunan, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China., Zeng C; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China., Lei G; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China.
Source: Clinical orthopaedics and related research [Clin Orthop Relat Res] 2026 Apr 01; Vol. 484 (4), pp. 754-769. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 0075674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1132 (Electronic) Linking ISSN: 0009921X NLM ISO Abbreviation: Clin Orthop Relat Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Which Analgesic Should We Use to Relieve Pain After Knee or Hip Arthroplasty? A Systematic Review and Network Meta-analysis of RCTs.
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  Data: <searchLink fieldCode="AU" term="%22He+H%22">He H</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Wen+Z%22">Wen Z</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK.; Pain Centre Versus Arthritis, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Doherty+M%22">Doherty M</searchLink>; Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK.; Pain Centre Versus Arthritis, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xie+J%22">Xie J</searchLink>; Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Xie+D%22">Xie D</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Wei+J%22">Wei J</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, PR China.; FuRong Laboratory, Changsha, Hunan, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Zeng+C%22">Zeng C</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China.<br /><searchLink fieldCode="AU" term="%22Lei+G%22">Lei G</searchLink>; Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, PR China.; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, PR China.; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, PR China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, PR China.
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