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Dynamic rRNA methylation regulates translation in the hematopoietic system and is essential for stem cell fitness.

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Title: Dynamic rRNA methylation regulates translation in the hematopoietic system and is essential for stem cell fitness.
Authors: Rabany O; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Ben Dror S; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Arafat M; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Aharoni Levitanus H; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Halperin Y; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Marchand V; UAR2008 Ingenierie Biologie Santé En Lorraine CNRS-INSERM, Université de Lorraine, Nancy, France., Romanovski N; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Ussishkin N; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Livneh Golany M; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Reches A; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Wexler J; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Mayorek N; The Concern Foundation Laboratories at The Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research, Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Monderer-Rothkoff G; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Shifman S; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Bouhou WM; Oncode Institute, Utrecht, The Netherlands.; Hubrecht Institute, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands., VanInsberghe M; Oncode Institute, Utrecht, The Netherlands.; Hubrecht Institute, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands., Pauli C; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany., Müller-Tidow C; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.; German Cancer Research Center Heidelberg and Medical Faculty Heidelberg University, Heidelberg, Germany., Karmi O; Research Infrastructure Core Facility, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Jerusalem, Israel., Livneh Y; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel., van Oudenaarden A; Oncode Institute, Utrecht, The Netherlands., Motorin Y; UAR2008 Ingenierie Biologie Santé En Lorraine CNRS-INSERM, Université de Lorraine, Nancy, France.; UMR7365 Ingenierie Moleculaire, Cellulaire et Physiopathologie, CNRS, Université de Lorraine, Nancy, France., Nachmani D; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
Source: Blood [Blood] 2026 Jan 29; Vol. 147 (5), pp. 520-533.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dynamic rRNA methylation regulates translation in the hematopoietic system and is essential for stem cell fitness.
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  Data: <searchLink fieldCode="AU" term="%22Rabany+O%22">Rabany O</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Ben+Dror+S%22">Ben Dror S</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Arafat+M%22">Arafat M</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Aharoni+Levitanus+H%22">Aharoni Levitanus H</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Halperin+Y%22">Halperin Y</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Marchand+V%22">Marchand V</searchLink>; UAR2008 Ingenierie Biologie Santé En Lorraine CNRS-INSERM, Université de Lorraine, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Romanovski+N%22">Romanovski N</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Ussishkin+N%22">Ussishkin N</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Livneh+Golany+M%22">Livneh Golany M</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Reches+A%22">Reches A</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Wexler+J%22">Wexler J</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Mayorek+N%22">Mayorek N</searchLink>; The Concern Foundation Laboratories at The Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research, Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Monderer-Rothkoff+G%22">Monderer-Rothkoff G</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Shifman+S%22">Shifman S</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Bouhou+WM%22">Bouhou WM</searchLink>; Oncode Institute, Utrecht, The Netherlands.; Hubrecht Institute, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22VanInsberghe+M%22">VanInsberghe M</searchLink>; Oncode Institute, Utrecht, The Netherlands.; Hubrecht Institute, Utrecht, The Netherlands.; University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pauli+C%22">Pauli C</searchLink>; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Tidow+C%22">Müller-Tidow C</searchLink>; Department of Medicine V, Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.; German Cancer Research Center Heidelberg and Medical Faculty Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Karmi+O%22">Karmi O</searchLink>; Research Infrastructure Core Facility, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Livneh+Y%22">Livneh Y</searchLink>; Department of Brain Sciences, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22van+Oudenaarden+A%22">van Oudenaarden A</searchLink>; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Motorin+Y%22">Motorin Y</searchLink>; UAR2008 Ingenierie Biologie Santé En Lorraine CNRS-INSERM, Université de Lorraine, Nancy, France.; UMR7365 Ingenierie Moleculaire, Cellulaire et Physiopathologie, CNRS, Université de Lorraine, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Nachmani+D%22">Nachmani D</searchLink>; Department of Genetics, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
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        Value: 10.1182/blood.2024028300
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        Text: English
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