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Efficacy of Neratinib-Based Therapy in ERBB2-Mutant Lung Adenocarcinomas: Findings From 2 International Phase 2 Studies.

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Title: Efficacy of Neratinib-Based Therapy in ERBB2-Mutant Lung Adenocarcinomas: Findings From 2 International Phase 2 Studies.
Authors: Li BT; Memorial Sloan Kettering Cancer Center, New York, NY., Gandhi L; Dana-Farber Cancer Institute, Boston, MA., Ravichandran V; Memorial Sloan Kettering Cancer Center, New York, NY., Besse B; Gustave Roussy, Paris Saclay University, Villejuif, France., Mazières J; Hôpital Universitaire de Toulouse, Université Paul Sabatier, Toulouse, France., Shapiro GI; Dana-Farber Cancer Institute, Boston, MA., Boni V; NEXT Madrid, University Hospital Quironsalud, Pozuelo de Alarcón, Madrid, Spain., Waqar SN; Washington University School of Medicine in St Louis, St. Louis, MO., Park H; Washington University School of Medicine in St Louis, St. Louis, MO., Quinn DI; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA., Martinez A; Instituto Oncológico Dr Rosell, Hospital Universitario Dexeus, Grupo Quiron Salud, Les Corts, Barcelona, Spain., Stemmer SM; Davidoff Center, Rabin Medical Center and Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel., Cortot AB; University of Lille, CHU Lille, CNRS, Inserm, Institut Pasteur de Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity, Plasticity and Resistance to Therapies, Lille, France., Barlesi F; University Paris Saclay, France., Quoix E; UNISTRA, Strasbourg, Strasbourg, France., Burkard ME; University of Wisconsin, Madison WI., Selcuklu SD; Memorial Sloan Kettering Cancer Center, New York, NY., Hunt C; Memorial Sloan Kettering Cancer Center, New York, NY., Donoghue MTA; Memorial Sloan Kettering Cancer Center, New York, NY., Kris MG; Memorial Sloan Kettering Cancer Center, New York, NY., Bebchuk J; Puma Biotechnology, Inc., Los Angeles, CA., Eli LD; Puma Biotechnology, Inc., Los Angeles, CA., McCulloch L; Puma Biotechnology, Inc., Los Angeles, CA., Solit DB; Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: solitd@mskcc.org., Jänne PA; Dana-Farber Cancer Institute, Boston, MA.
Source: Clinical lung cancer [Clin Lung Cancer] 2026 Mar; Vol. 27 (2), pp. 214-226.e5. Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100893225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-0690 (Electronic) Linking ISSN: 15257304 NLM ISO Abbreviation: Clin Lung Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy of Neratinib-Based Therapy in ERBB2-Mutant Lung Adenocarcinomas: Findings From 2 International Phase 2 Studies.
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  Data: <searchLink fieldCode="AU" term="%22Li+BT%22">Li BT</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Gandhi+L%22">Gandhi L</searchLink>; Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Ravichandran+V%22">Ravichandran V</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Besse+B%22">Besse B</searchLink>; Gustave Roussy, Paris Saclay University, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Mazières+J%22">Mazières J</searchLink>; Hôpital Universitaire de Toulouse, Université Paul Sabatier, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Shapiro+GI%22">Shapiro GI</searchLink>; Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Boni+V%22">Boni V</searchLink>; NEXT Madrid, University Hospital Quironsalud, Pozuelo de Alarcón, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Waqar+SN%22">Waqar SN</searchLink>; Washington University School of Medicine in St Louis, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Park+H%22">Park H</searchLink>; Washington University School of Medicine in St Louis, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Quinn+DI%22">Quinn DI</searchLink>; University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Martinez+A%22">Martinez A</searchLink>; Instituto Oncológico Dr Rosell, Hospital Universitario Dexeus, Grupo Quiron Salud, Les Corts, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Stemmer+SM%22">Stemmer SM</searchLink>; Davidoff Center, Rabin Medical Center and Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel.<br /><searchLink fieldCode="AU" term="%22Cortot+AB%22">Cortot AB</searchLink>; University of Lille, CHU Lille, CNRS, Inserm, Institut Pasteur de Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity, Plasticity and Resistance to Therapies, Lille, France.<br /><searchLink fieldCode="AU" term="%22Barlesi+F%22">Barlesi F</searchLink>; University Paris Saclay, France.<br /><searchLink fieldCode="AU" term="%22Quoix+E%22">Quoix E</searchLink>; UNISTRA, Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Burkard+ME%22">Burkard ME</searchLink>; University of Wisconsin, Madison WI.<br /><searchLink fieldCode="AU" term="%22Selcuklu+SD%22">Selcuklu SD</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Hunt+C%22">Hunt C</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Donoghue+MTA%22">Donoghue MTA</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Kris+MG%22">Kris MG</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Bebchuk+J%22">Bebchuk J</searchLink>; Puma Biotechnology, Inc., Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Eli+LD%22">Eli LD</searchLink>; Puma Biotechnology, Inc., Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22McCulloch+L%22">McCulloch L</searchLink>; Puma Biotechnology, Inc., Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Solit+DB%22">Solit DB</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: solitd@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Jänne+PA%22">Jänne PA</searchLink>; Dana-Farber Cancer Institute, Boston, MA.
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  Data: <searchLink fieldCode="JN" term="%22100893225%22">Clinical lung cancer</searchLink> [Clin Lung Cancer] 2026 Mar; Vol. 27 (2), pp. 214-226.e5. <i>Date of Electronic Publication: </i>2025 Oct 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100893225 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1938-0690 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215257304%22">15257304 </searchLink><i>NLM ISO Abbreviation: </i>Clin Lung Cancer <i>Subsets: </i>MEDLINE
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