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Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia on Ibrutinib Therapy: Results from a Phase Ib Study.

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Title: Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia on Ibrutinib Therapy: Results from a Phase Ib Study.
Authors: Rogers KA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Yan P; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Flinn IW; Tennessee Oncology and One Oncology, Nashville, Tennessee., Stephens DM; Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, North Carolina., Kipps TJ; UC San Diego, Moores Cancer Center, La Jolla, California., Larson SM; Ronald Reagan UCLA Medical Center, Los Angeles, California., Martz L; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Chen X; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Wang H; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Hopping E; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Bundschuh R; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; Department of Physics, The Ohio State University, Columbus, Ohio.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio., Turkoglu A; Department of Electrical & Computer Engineering, The Ohio State University, Columbus, Ohio.; The Ohio State University Comprehensive Cancer Center, James Cancer Hospital and Solove Research Institute, Columbus, Ohio., Lozanski G; Department of Pathology, The Ohio State University, Columbus, Ohio., McGarry C; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey., Acosta A; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey., Sechaud R; Biomedical Research, Novartis Pharma AG, Basel, Switzerland., Baldoni D; Biomedical Research, Novartis Pharma AG, Basel, Switzerland., Chaudhury A; Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts., Whalen J; Biomedical Research, Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts., Hassounah NB; Biomedical Research, Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts., Orwitz N; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey., Otero J; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey., Woo J; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey., Byrd JC; Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Dec 15; Vol. 31 (24), pp. 5145-5158.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia on Ibrutinib Therapy: Results from a Phase Ib Study.
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  Data: <searchLink fieldCode="AU" term="%22Rogers+KA%22">Rogers KA</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Yan+P%22">Yan P</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Flinn+IW%22">Flinn IW</searchLink>; Tennessee Oncology and One Oncology, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Stephens+DM%22">Stephens DM</searchLink>; Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, North Carolina.<br /><searchLink fieldCode="AU" term="%22Kipps+TJ%22">Kipps TJ</searchLink>; UC San Diego, Moores Cancer Center, La Jolla, California.<br /><searchLink fieldCode="AU" term="%22Larson+SM%22">Larson SM</searchLink>; Ronald Reagan UCLA Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Martz+L%22">Martz L</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Hopping+E%22">Hopping E</searchLink>; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Bundschuh+R%22">Bundschuh R</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; Department of Physics, The Ohio State University, Columbus, Ohio.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Turkoglu+A%22">Turkoglu A</searchLink>; Department of Electrical & Computer Engineering, The Ohio State University, Columbus, Ohio.; The Ohio State University Comprehensive Cancer Center, James Cancer Hospital and Solove Research Institute, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Lozanski+G%22">Lozanski G</searchLink>; Department of Pathology, The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22McGarry+C%22">McGarry C</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.<br /><searchLink fieldCode="AU" term="%22Acosta+A%22">Acosta A</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.<br /><searchLink fieldCode="AU" term="%22Sechaud+R%22">Sechaud R</searchLink>; Biomedical Research, Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Baldoni+D%22">Baldoni D</searchLink>; Biomedical Research, Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chaudhury+A%22">Chaudhury A</searchLink>; Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Whalen+J%22">Whalen J</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hassounah+NB%22">Hassounah NB</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Orwitz+N%22">Orwitz N</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.<br /><searchLink fieldCode="AU" term="%22Otero+J%22">Otero J</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.<br /><searchLink fieldCode="AU" term="%22Woo+J%22">Woo J</searchLink>; Biomedical Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.<br /><searchLink fieldCode="AU" term="%22Byrd+JC%22">Byrd JC</searchLink>; Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Dec 15; Vol. 31 (24), pp. 5145-5158.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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