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Transcranial ultrasound combined with intravenous metformin-loaded oxygenated microbubbles attenuates noise-induced hearing loss in mice.

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Title: Transcranial ultrasound combined with intravenous metformin-loaded oxygenated microbubbles attenuates noise-induced hearing loss in mice.
Authors: Liao AH; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.; Department of Biomedical Engineering, National Defense Medical University, Taipei, Taiwan., Wang CH; Department of Otolaryngology, Taipei City Hospital, Taipei, Taiwan.; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical University, Taipei, Taiwan., Chou LY; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan., Hung YC; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan., Lin YC; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Chuang HC; Department of Mechanical Engineering, National Taipei University of Technology, Taipei, Taiwan., Ma KH; Department of Biology and Anatomy, National Defense Medical University, Taipei, Taiwan., Liu HL; Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan., Wang JK; Department of Biochemistry, National Defense Medical University, Taipei, Taiwan., Shih CP; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Source: Drug delivery [Drug Deliv] 2025 Dec 31; Vol. 32 (1), pp. 2576220. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcranial ultrasound combined with intravenous metformin-loaded oxygenated microbubbles attenuates noise-induced hearing loss in mice.
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  Data: <searchLink fieldCode="AU" term="%22Liao+AH%22">Liao AH</searchLink>; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.; Department of Biomedical Engineering, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CH%22">Wang CH</searchLink>; Department of Otolaryngology, Taipei City Hospital, Taipei, Taiwan.; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+LY%22">Chou LY</searchLink>; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hung+YC%22">Hung YC</searchLink>; Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YC%22">Lin YC</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuang+HC%22">Chuang HC</searchLink>; Department of Mechanical Engineering, National Taipei University of Technology, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ma+KH%22">Ma KH</searchLink>; Department of Biology and Anatomy, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+HL%22">Liu HL</searchLink>; Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JK%22">Wang JK</searchLink>; Department of Biochemistry, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+CP%22">Shih CP</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%229417471%22">Drug delivery</searchLink> [Drug Deliv] 2025 Dec 31; Vol. 32 (1), pp. 2576220. <i>Date of Electronic Publication: </i>2025 Nov 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9417471 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-0464 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210717544%22">10717544 </searchLink><i>NLM ISO Abbreviation: </i>Drug Deliv <i>Subsets: </i>MEDLINE
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              Text: 2025 Dec 31
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