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Platelet-rich plasma mitigates lipopolysaccharide-driven acute lung injury by targeting the cGAS-induced STING/ERS/TBK1/IRF3/NF-κB pathway in male rats.

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Title: Platelet-rich plasma mitigates lipopolysaccharide-driven acute lung injury by targeting the cGAS-induced STING/ERS/TBK1/IRF3/NF-κB pathway in male rats.
Authors: Hassan FE; Medical Physiology Department, Kasr Alainy, Faculty of Medicine, Cairo University, Giza, 11562, Egypt. Fatma.e.elsayed@kasralainy.edu.eg.; Department of Physiology, General Medicine Practice Program, Batterjee Medical College, 21442, Jeddah, Saudi Arabia. Fatma.e.elsayed@kasralainy.edu.eg., Elgilil NMA; Medical Physiology Department, Kasr Alainy, Faculty of Medicine, Cairo University, Giza, 11562, Egypt., Aboulhoda BE; Anatomy and Embryology Department, Faculty of Medicine, Cairo University, Giza, Egypt., Abdallah HA; Anatomy and Embryology Department, Faculty of Medicine, Cairo University, Giza, Egypt.; Department of Anatomy, King Khalid University, 62529, Abha, Saudi Arabia., Rashed LA; Department of Medical Biochemistry and Molecular Biology, Kasr Alainy, Faculty of Medicine, Cairo University, Giza, 11562, Egypt., Shaban SM; Medical Physiology Department, Kasr Alainy, Faculty of Medicine, Cairo University, Giza, 11562, Egypt.
Source: Histochemistry and cell biology [Histochem Cell Biol] 2025 Nov 06; Vol. 163 (1), pp. 102. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9506663 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-119X (Electronic) Linking ISSN: 09486143 NLM ISO Abbreviation: Histochem Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-119X
DOI:10.1007/s00418-025-02427-9