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In situ gut microbiota editing: enhancing therapeutic efficacy for bacterial colitis by compatible oral hydrogel microspheres with phages.

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Title: In situ gut microbiota editing: enhancing therapeutic efficacy for bacterial colitis by compatible oral hydrogel microspheres with phages.
Authors: Yang Y; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China., Li R; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China., Zhong Q; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China., Guo Y; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China., Wu R; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China., Chen H; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China., Zhou R; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China., Ye R; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Chemistry, Huazhong Agricultural University, Wuhan, China., Dąbrowska K; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Faculty of Medicine, Wrocław University of Science and Technology, Wrocław, Poland., Prajsnar TK; Department of Evolutionary Immunology, Jagiellonian University, Kraków, Poland., Stafford GP; School of Clinical Dentistry, The University of Sheffield, Sheffield, United Kingdom., Zou G; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China. zougeng19900918@126.com., Zhou Y; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. zhouyang@mail.hzau.edu.cn.; College of Fisheries, Huazhong Agricultural University, Wuhan, China. zhouyang@mail.hzau.edu.cn., Li J; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. lijinquan2007@gmail.com.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China. lijinquan2007@gmail.com.; Hubei Jiangxia Laboratory, Wuhan, China. lijinquan2007@gmail.com.; Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, NY, USA. lijinquan2007@gmail.com.; Zhanjiang Key Laboratory of Metabolic Disease Research, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. lijinquan2007@gmail.com., Song Z; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.; College of Chemistry, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.
Source: Nature communications [Nat Commun] 2025 Nov 06; Vol. 16 (1), pp. 9785. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In situ gut microbiota editing: enhancing therapeutic efficacy for bacterial colitis by compatible oral hydrogel microspheres with phages.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Life Science and Technology, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhong+Q%22">Zhong Q</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wu+R%22">Wu R</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhou+R%22">Zhou R</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Ye+R%22">Ye R</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China.; College of Chemistry, Huazhong Agricultural University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Dąbrowska+K%22">Dąbrowska K</searchLink>; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Faculty of Medicine, Wrocław University of Science and Technology, Wrocław, Poland.<br /><searchLink fieldCode="AU" term="%22Prajsnar+TK%22">Prajsnar TK</searchLink>; Department of Evolutionary Immunology, Jagiellonian University, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Stafford+GP%22">Stafford GP</searchLink>; School of Clinical Dentistry, The University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zou+G%22">Zou G</searchLink>; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China. zougeng19900918@126.com.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. zhouyang@mail.hzau.edu.cn.; College of Fisheries, Huazhong Agricultural University, Wuhan, China. zhouyang@mail.hzau.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. lijinquan2007@gmail.com.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China. lijinquan2007@gmail.com.; Hubei Jiangxia Laboratory, Wuhan, China. lijinquan2007@gmail.com.; Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, NY, USA. lijinquan2007@gmail.com.; Zhanjiang Key Laboratory of Metabolic Disease Research, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China. lijinquan2007@gmail.com.<br /><searchLink fieldCode="AU" term="%22Song+Z%22">Song Z</searchLink>; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Environment Correlative Dietology, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.; Hubei Hongshan Laboratory, College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.; College of Chemistry, Huazhong Agricultural University, Wuhan, China. songzhiyong@mail.hzau.edu.cn.
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