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An ATP-gated molecular switch orchestrates human mRNA export.

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Title: An ATP-gated molecular switch orchestrates human mRNA export.
Authors: Hohmann U; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. u.hohmann@imb-mainz.de.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. u.hohmann@imb-mainz.de.; Institute of Molecular Biology (IMB), Mainz, Germany. u.hohmann@imb-mainz.de., Graf M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria., Tirián L; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Pacheco-Fiallos B; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria., Schellhaas U; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria., Fin L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Handler D; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Phillips AW; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Riabov-Bassat D; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Faraway R; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Max Perutz Labs, Vienna BioCenter (VBC), Vienna, Austria.; University of Vienna, Max Perutz Labs, Department of Biochemistry and Cell Biology, Vienna, Austria., Pühringer T; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Szalay MF; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Roitinger E; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Brennecke J; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. julius.brennecke@imba.oeaw.ac.at., Plaschka C; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at.
Source: Nature [Nature] 2026 Jan; Vol. 649 (8098), pp. 1042-1050. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An ATP-gated molecular switch orchestrates human mRNA export.
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  Data: <searchLink fieldCode="AU" term="%22Hohmann+U%22">Hohmann U</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. u.hohmann@imb-mainz.de.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. u.hohmann@imb-mainz.de.; Institute of Molecular Biology (IMB), Mainz, Germany. u.hohmann@imb-mainz.de.<br /><searchLink fieldCode="AU" term="%22Graf+M%22">Graf M</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Tirián+L%22">Tirián L</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Pacheco-Fiallos+B%22">Pacheco-Fiallos B</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schellhaas+U%22">Schellhaas U</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Fin+L%22">Fin L</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Handler+D%22">Handler D</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Phillips+AW%22">Phillips AW</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Riabov-Bassat+D%22">Riabov-Bassat D</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Faraway+R%22">Faraway R</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Max Perutz Labs, Vienna BioCenter (VBC), Vienna, Austria.; University of Vienna, Max Perutz Labs, Department of Biochemistry and Cell Biology, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Pühringer+T%22">Pühringer T</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Szalay+MF%22">Szalay MF</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Roitinger+E%22">Roitinger E</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brennecke+J%22">Brennecke J</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. julius.brennecke@imba.oeaw.ac.at.<br /><searchLink fieldCode="AU" term="%22Plaschka+C%22">Plaschka C</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Jan; Vol. 649 (8098), pp. 1042-1050. <i>Date of Electronic Publication: </i>2025 Nov 06.
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