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Unraveling spatiotemporal dynamics in transdiagnosis subtypes of major depressive disorder and bipolar disorder: insights from co-activation patterns and treatment response.

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Title: Unraveling spatiotemporal dynamics in transdiagnosis subtypes of major depressive disorder and bipolar disorder: insights from co-activation patterns and treatment response.
Authors: Cai A; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.; The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, P.R. China.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China.; Songjiang Hospital and Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China., Yang J; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Guo H; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China., Dong S; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China., Zhao T; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Zhou W; Songjiang Hospital and Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China., Hou M; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Zheng J; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Liu J; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Tang Y; Department of Psychiatry, Shengjing Hospital of China Medical University, Shenyang, P.R. China., Zhu R; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China., Ni X; The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, P.R. China. nxy@njmu.edu.cn.; Department of Radiotherapy, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, P.R. China. nxy@njmu.edu.cn., Zhang X; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China. zhangxizhe@gmail.com.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China. zhangxizhe@gmail.com., Gong X; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, P.R. China. gongxh@fudan.edu.cn., Wang F; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.; Department of Mental Health, School of Public Health, Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.; Functional Brain Imaging Institute of Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Mar; Vol. 31 (3), pp. 1810-1822. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cai+A%22">Cai A</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.; The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, P.R. China.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China.; Songjiang Hospital and Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Dong+S%22">Dong S</searchLink>; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhao+T%22">Zhao T</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Songjiang Hospital and Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.<br /><searchLink fieldCode="AU" term="%22Hou+M%22">Hou M</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Department of Psychiatry, Shengjing Hospital of China Medical University, Shenyang, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhu+R%22">Zhu R</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China.<br /><searchLink fieldCode="AU" term="%22Ni+X%22">Ni X</searchLink>; The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, P.R. China. nxy@njmu.edu.cn.; Department of Radiotherapy, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, P.R. China. nxy@njmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China. zhangxizhe@gmail.com.; School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, P.R. China. zhangxizhe@gmail.com.<br /><searchLink fieldCode="AU" term="%22Gong+X%22">Gong X</searchLink>; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, P.R. China. gongxh@fudan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+F%22">Wang F</searchLink>; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.; Department of Mental Health, School of Public Health, Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.; Functional Brain Imaging Institute of Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Mar; Vol. 31 (3), pp. 1810-1822. <i>Date of Electronic Publication: </i>2025 Nov 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41380-025-03326-0
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        Text: English
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              Text: 2026 Mar
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