Loss of ADAM17 in smooth muscle cells enhances their transformation to macrophage-like cells leading to more severe atherosclerosis in mice.

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Bibliographic Details
Title: Loss of ADAM17 in smooth muscle cells enhances their transformation to macrophage-like cells leading to more severe atherosclerosis in mice.
Authors: Meganathan I; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Kilic T; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Al Rimon R; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Naiya T; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Krishnan V; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Atanasova N; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Wong A; University Health Network, Department of Immunology, University of Toronto, Toronto, ON, Canada; Ted Rogers Centre for Heart Research at the Peter Munk Cardiac Centre, Canada., Oudit GY; Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada., Epelman S; University Health Network, Department of Immunology, University of Toronto, Toronto, ON, Canada; Ted Rogers Centre for Heart Research at the Peter Munk Cardiac Centre, Canada., Kassiri Z; Department of Physiology, Cardiovascular Research Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address: z.kassiri@ualberta.ca.
Source: Atherosclerosis [Atherosclerosis] 2025 Dec; Vol. 411, pp. 120567. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-1484
DOI:10.1016/j.atherosclerosis.2025.120567