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Amyotrophic Lateral Sclerosis Clinical Research Site Operations: Emerging Challenges and Potential Solutions From Multiple Sites in the US.

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Title: Amyotrophic Lateral Sclerosis Clinical Research Site Operations: Emerging Challenges and Potential Solutions From Multiple Sites in the US.
Authors: Scirocco E; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Luppino SD; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Allen MD; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Giacomelli E; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Gelevski D; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Higgins M; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Scalia JL; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., McCaffrey AC; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sanders DL; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ho DT; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Quarles B; Department of Neurology and Neurosurgery, Augusta University, Augusta, Georgia, USA., Dalamagas H; Hospital for Special Care, New Britain, Connecticut, USA., Heintzman S; Division of Neuromuscular Disorders, Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA., Paganoni S; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA.
Source: Muscle & nerve [Muscle Nerve] 2026 Jan; Vol. 73 (1), pp. 28-33. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Scirocco+E%22">Scirocco E</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Luppino+SD%22">Luppino SD</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Allen+MD%22">Allen MD</searchLink>; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Giacomelli+E%22">Giacomelli E</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gelevski+D%22">Gelevski D</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Higgins+M%22">Higgins M</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Scalia+JL%22">Scalia JL</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22McCaffrey+AC%22">McCaffrey AC</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+DL%22">Sanders DL</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ho+DT%22">Ho DT</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Quarles+B%22">Quarles B</searchLink>; Department of Neurology and Neurosurgery, Augusta University, Augusta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Dalamagas+H%22">Dalamagas H</searchLink>; Hospital for Special Care, New Britain, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Heintzman+S%22">Heintzman S</searchLink>; Division of Neuromuscular Disorders, Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Paganoni+S%22">Paganoni S</searchLink>; Department of Neurology, Sean M. Healey and AMG Center for ALS and the Neurological Clinical Research Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA.
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              Text: 2026 Jan
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