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Dapagliflozin ameliorates cisplatin-induced cognitive impairments in rats: Cross-talk between miRNA-21/p-ERK/p-38 MAPK and wnt/β-catenin signaling pathways.

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Title: Dapagliflozin ameliorates cisplatin-induced cognitive impairments in rats: Cross-talk between miRNA-21/p-ERK/p-38 MAPK and wnt/β-catenin signaling pathways.
Authors: Shaheen AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt., Sayed RH; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt., Helal GK; Pharmacology and Toxicology Department, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt., El-Yamany MF; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt., Fahmy MI; Pharmacology and Toxicology Department, College of Pharmaceutical Sciences and drug manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt. Electronic address: mohamed.aljawaly@must.edu.eg.
Source: Neurotoxicology [Neurotoxicology] 2025 Dec; Vol. 111, pp. 103348. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7905589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9711 (Electronic) Linking ISSN: 0161813X NLM ISO Abbreviation: Neurotoxicology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dapagliflozin ameliorates cisplatin-induced cognitive impairments in rats: Cross-talk between miRNA-21/p-ERK/p-38 MAPK and wnt/β-catenin signaling pathways.
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  Data: <searchLink fieldCode="AU" term="%22Shaheen+AM%22">Shaheen AM</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt.<br /><searchLink fieldCode="AU" term="%22Sayed+RH%22">Sayed RH</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Helal+GK%22">Helal GK</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Yamany+MF%22">El-Yamany MF</searchLink>; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Fahmy+MI%22">Fahmy MI</searchLink>; Pharmacology and Toxicology Department, College of Pharmaceutical Sciences and drug manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt. Electronic address: mohamed.aljawaly@must.edu.eg.
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  Data: <searchLink fieldCode="JN" term="%227905589%22">Neurotoxicology</searchLink> [Neurotoxicology] 2025 Dec; Vol. 111, pp. 103348. <i>Date of Electronic Publication: </i>2025 Nov 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7905589 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9711 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220161813X%22">0161813X </searchLink><i>NLM ISO Abbreviation: </i>Neurotoxicology <i>Subsets: </i>MEDLINE
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