Impact of whole-brain radiation therapy on neurocognitive functions, alopecia and hearing loss: a systematic review and meta-analysis endorsed by the Palliative Care and Neuro-Oncology Study Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO).
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| Title: | Impact of whole-brain radiation therapy on neurocognitive functions, alopecia and hearing loss: a systematic review and meta-analysis endorsed by the Palliative Care and Neuro-Oncology Study Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO). |
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| Authors: | Di Franco R; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy., Pezzulla D; Radiation Oncology Unit, Responsible Research Hospital, Campobasso, Molise, Italy. pezzulla.donato@libero.it., Chiesa S; UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy., Cellini F; UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy.; Dipartimento Universitario Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Università Cattolica del Sacro Cuore, Rome, Italy., Rocchi E; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Peluso S; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Maurizi F; Radiation Oncology, Azienda Sanitaria Territoriale (AST) PU, Ospedale San Salvatore (St. Muraglia), Pesaro, Italy., Borzillo V; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy., Scipilliti E; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy., Bonzano E; Department of Radiation Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Matteo Polyclinic Foundation, Pavia, Italy., Colombo S; Division of Radiation Oncology, Department of Hemato-Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Cacciola A; Radiation Oncology Unit, A.O.U. 'G. Martino', Messina, Italy., Mazzola GC; Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy., Bergamaschi L; Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy., Lillo S; Radiation Oncology Unit, Clinical Department, National Center for Oncological Hadrontherapy (CNAO), 27100, Pavia, Italy.; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy., De Cicco L; Division of Radiation Oncology, ASST of Olona Valley, Busto Arsizio, Italy., Argenone A; Division of Radiation Oncology, Azienda Ospedaliera di Rilievo Nazionale San Pio, Benevento, Italy., Arcidiacono F; Radiotherapy Oncology Centre, 'S. Maria' Hospital, Terni, Italy., Muto P; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy., Deodato F; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.; Istituto di Radiologia, Universita Cattolica del Sacro Cuore, Rome, Italy., Pinzi V; Radiotherapy Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy., Maranzano E; University of Perugia, Perugia, Italy. |
| Source: | La Radiologia medica [Radiol Med] 2026 Mar; Vol. 131 (3), pp. 508-530. Date of Electronic Publication: 2025 Nov 08. |
| Publication Type: | Journal Article; Systematic Review; Meta-Analysis; Review |
| Journal Info: | Publisher: Springer Milan Country of Publication: Italy NLM ID: 0177625 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1826-6983 (Electronic) Linking ISSN: 00338362 NLM ISO Abbreviation: Radiol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41206407 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Impact of whole-brain radiation therapy on neurocognitive functions, alopecia and hearing loss: a systematic review and meta-analysis endorsed by the Palliative Care and Neuro-Oncology Study Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Di+Franco+R%22">Di Franco R</searchLink>; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pezzulla+D%22">Pezzulla D</searchLink>; Radiation Oncology Unit, Responsible Research Hospital, Campobasso, Molise, Italy. pezzulla.donato@libero.it.<br /><searchLink fieldCode="AU" term="%22Chiesa+S%22">Chiesa S</searchLink>; UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cellini+F%22">Cellini F</searchLink>; UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy.; Dipartimento Universitario Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rocchi+E%22">Rocchi E</searchLink>; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Peluso+S%22">Peluso S</searchLink>; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Maurizi+F%22">Maurizi F</searchLink>; Radiation Oncology, Azienda Sanitaria Territoriale (AST) PU, Ospedale San Salvatore (St. Muraglia), Pesaro, Italy.<br /><searchLink fieldCode="AU" term="%22Borzillo+V%22">Borzillo V</searchLink>; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Scipilliti+E%22">Scipilliti E</searchLink>; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bonzano+E%22">Bonzano E</searchLink>; Department of Radiation Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Matteo Polyclinic Foundation, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Colombo+S%22">Colombo S</searchLink>; Division of Radiation Oncology, Department of Hemato-Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Cacciola+A%22">Cacciola A</searchLink>; Radiation Oncology Unit, A.O.U. 'G. Martino', Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzola+GC%22">Mazzola GC</searchLink>; Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bergamaschi+L%22">Bergamaschi L</searchLink>; Division of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lillo+S%22">Lillo S</searchLink>; Radiation Oncology Unit, Clinical Department, National Center for Oncological Hadrontherapy (CNAO), 27100, Pavia, Italy.; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22De+Cicco+L%22">De Cicco L</searchLink>; Division of Radiation Oncology, ASST of Olona Valley, Busto Arsizio, Italy.<br /><searchLink fieldCode="AU" term="%22Argenone+A%22">Argenone A</searchLink>; Division of Radiation Oncology, Azienda Ospedaliera di Rilievo Nazionale San Pio, Benevento, Italy.<br /><searchLink fieldCode="AU" term="%22Arcidiacono+F%22">Arcidiacono F</searchLink>; Radiotherapy Oncology Centre, 'S. Maria' Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Muto+P%22">Muto P</searchLink>; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Deodato+F%22">Deodato F</searchLink>; Department of Radiation Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.; Istituto di Radiologia, Universita Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pinzi+V%22">Pinzi V</searchLink>; Radiotherapy Unit, Fondazione IRCCS Istituto Neurologico 'Carlo Besta', Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Maranzano+E%22">Maranzano E</searchLink>; University of Perugia, Perugia, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220177625%22">La Radiologia medica</searchLink> [Radiol Med] 2026 Mar; Vol. 131 (3), pp. 508-530. <i>Date of Electronic Publication: </i>2025 Nov 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Systematic Review; Meta-Analysis; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Milan%22">Springer Milan </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>0177625 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1826-6983 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200338362%22">00338362 </searchLink><i>NLM ISO Abbreviation: </i>Radiol Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41206407 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11547-025-02143-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 508 Titles: – TitleFull: Impact of whole-brain radiation therapy on neurocognitive functions, alopecia and hearing loss: a systematic review and meta-analysis endorsed by the Palliative Care and Neuro-Oncology Study Groups of the Italian Association of Radiotherapy and Clinical Oncology (AIRO). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Di Franco R – PersonEntity: Name: NameFull: Pezzulla D – PersonEntity: Name: NameFull: Chiesa S – PersonEntity: Name: NameFull: Cellini F – PersonEntity: Name: NameFull: Rocchi E – PersonEntity: Name: NameFull: Peluso S – PersonEntity: Name: NameFull: Maurizi F – PersonEntity: Name: NameFull: Borzillo V – PersonEntity: Name: NameFull: Scipilliti E – PersonEntity: Name: NameFull: Bonzano E – PersonEntity: Name: NameFull: Colombo S – PersonEntity: Name: NameFull: Cacciola A – PersonEntity: Name: NameFull: Mazzola GC – PersonEntity: Name: NameFull: Bergamaschi L – PersonEntity: Name: NameFull: Lillo S – PersonEntity: Name: NameFull: De Cicco L – PersonEntity: Name: NameFull: Argenone A – PersonEntity: Name: NameFull: Arcidiacono F – PersonEntity: Name: NameFull: Muto P – PersonEntity: Name: NameFull: Deodato F – PersonEntity: Name: NameFull: Pinzi V – PersonEntity: Name: NameFull: Maranzano E IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1826-6983 Numbering: – Type: volume Value: 131 – Type: issue Value: 3 Titles: – TitleFull: La Radiologia medica Type: main |
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