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Haematotoxicity of Craniospinal Radiochemotherapy for Metastatic Paediatric High-Grade Glioma.

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Title: Haematotoxicity of Craniospinal Radiochemotherapy for Metastatic Paediatric High-Grade Glioma.
Authors: Valentini C; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: Chiara.Valentini@uniklinikum-dresden.de., Perwein T; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria., Bison B; Diagnostik and Interventional Neuroradiology, Faculty of Medicine, University Augsburg, Neuroradiological Reference Center for the Pediatric Brain Tumor (HIT) Studies of the German Society of Pediatric Oncology and Hematology, Augsburg, Germany., Gielen GH; Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany., Knerlich-Lukoschus F; Department of Neurosurgery, Section Pediatric Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Bock HC; Department of Neurosurgery, Section Pediatric Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Seidel C; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany., Kortmann RD; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany., Sturm D; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Benesch M; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria., Nussbaumer G; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria., Krischer JM; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., von Bueren AO; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva, Switzerland; Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Eyrich M; University Children's Hospital, University Hospital Würzburg, Würzburg, Germany., Friker LL; Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany., Hoffmann M; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Gkika E; Department of Radiation Oncology, University Hospital Bonn, 53127, Bonn, Germany., Wittig-Sauerwein A; Department of Radiation Oncology, University of Würzburg, Würzburg, Germany., Hörner-Rieber J; Department of Radiation Oncology, University Hospital Düsseldorf, Düsseldorf, Germany., Schwarz R; Department for Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Jablonska K; Department of Radiation Oncology, CyberKnife and Radiation Therapy, Centre for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany., Hoffmann W; Clinic for Radio-Oncology and Radiotherapy, Braunschweig Municipal Hospital, Germany., Vordermark D; Department of Radiation Oncology, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany., Rieken S; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Höng L; Department of Radiation Oncology, Giessen-Marburg University Hospital, Giessen, Germany., Rödel C; Department of Radiotherapy of Oncology, University of Frankfurt, Frankfurt, Germany., Timmermann B; Department of Particle Therapy, University Hospital Essen, West German Proton Therapy Centre Essen (WPE), West German Cancer Centre (WTZ), Essen, Germany; German Cancer Consortium (DKTK), Essen, Germany., Fennell JT; Department of Radiation Oncology, University Medical Center Freiburg, Germany., Claviez A; Paediatric Oncology and Haematology Centre for Paediatrics Hannover Medical School, Germany., Karremann M; Department of Pediatric and Adolescent Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kramm CM; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Krause M; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany; OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum, Germany; Translational Radiooncology and Clinical Radiotherapy, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany; Translational Radiation Oncology, National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany; Translational Radiooncology and Clinical Radiotherapy and Image-guided High Precision Radiotherapy, German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; GermanTranslational Radiooncology and Clinical Radiotherapy and Image-guided High Precision Radiotherapy, Helmholtz Association / Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany; School of Medicine, Technische Universität Dresden, Dresden, Germany.
Source: Clinical oncology (Royal College of Radiologists (Great Britain)) [Clin Oncol (R Coll Radiol)] 2025 Dec; Vol. 48, pp. 103956. Date of Electronic Publication: 2025 Oct 11.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders Country of Publication: England NLM ID: 9002902 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-2981 (Electronic) Linking ISSN: 09366555 NLM ISO Abbreviation: Clin Oncol (R Coll Radiol) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Haematotoxicity of Craniospinal Radiochemotherapy for Metastatic Paediatric High-Grade Glioma.
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  Data: <searchLink fieldCode="AU" term="%22Valentini+C%22">Valentini C</searchLink>; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: Chiara.Valentini@uniklinikum-dresden.de.<br /><searchLink fieldCode="AU" term="%22Perwein+T%22">Perwein T</searchLink>; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Bison+B%22">Bison B</searchLink>; Diagnostik and Interventional Neuroradiology, Faculty of Medicine, University Augsburg, Neuroradiological Reference Center for the Pediatric Brain Tumor (HIT) Studies of the German Society of Pediatric Oncology and Hematology, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gielen+GH%22">Gielen GH</searchLink>; Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Knerlich-Lukoschus+F%22">Knerlich-Lukoschus F</searchLink>; Department of Neurosurgery, Section Pediatric Neurosurgery, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Bock+HC%22">Bock HC</searchLink>; Department of Neurosurgery, Section Pediatric Neurosurgery, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Seidel+C%22">Seidel C</searchLink>; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Kortmann+RD%22">Kortmann RD</searchLink>; Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Sturm+D%22">Sturm D</searchLink>; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Benesch+M%22">Benesch M</searchLink>; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Nussbaumer+G%22">Nussbaumer G</searchLink>; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Krischer+JM%22">Krischer JM</searchLink>; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22von+Bueren+AO%22">von Bueren AO</searchLink>; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva, Switzerland; Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Eyrich+M%22">Eyrich M</searchLink>; University Children's Hospital, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Friker+LL%22">Friker LL</searchLink>; Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+M%22">Hoffmann M</searchLink>; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gkika+E%22">Gkika E</searchLink>; Department of Radiation Oncology, University Hospital Bonn, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wittig-Sauerwein+A%22">Wittig-Sauerwein A</searchLink>; Department of Radiation Oncology, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hörner-Rieber+J%22">Hörner-Rieber J</searchLink>; Department of Radiation Oncology, University Hospital Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Schwarz+R%22">Schwarz R</searchLink>; Department for Radiotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jablonska+K%22">Jablonska K</searchLink>; Department of Radiation Oncology, CyberKnife and Radiation Therapy, Centre for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+W%22">Hoffmann W</searchLink>; Clinic for Radio-Oncology and Radiotherapy, Braunschweig Municipal Hospital, Germany.<br /><searchLink fieldCode="AU" term="%22Vordermark+D%22">Vordermark D</searchLink>; Department of Radiation Oncology, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.<br /><searchLink fieldCode="AU" term="%22Rieken+S%22">Rieken S</searchLink>; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Höng+L%22">Höng L</searchLink>; Department of Radiation Oncology, Giessen-Marburg University Hospital, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Rödel+C%22">Rödel C</searchLink>; Department of Radiotherapy of Oncology, University of Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Timmermann+B%22">Timmermann B</searchLink>; Department of Particle Therapy, University Hospital Essen, West German Proton Therapy Centre Essen (WPE), West German Cancer Centre (WTZ), Essen, Germany; German Cancer Consortium (DKTK), Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Fennell+JT%22">Fennell JT</searchLink>; Department of Radiation Oncology, University Medical Center Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Claviez+A%22">Claviez A</searchLink>; Paediatric Oncology and Haematology Centre for Paediatrics Hannover Medical School, Germany.<br /><searchLink fieldCode="AU" term="%22Karremann+M%22">Karremann M</searchLink>; Department of Pediatric and Adolescent Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Kramm+CM%22">Kramm CM</searchLink>; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Krause+M%22">Krause M</searchLink>; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany; OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum, Germany; Translational Radiooncology and Clinical Radiotherapy, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany; Translational Radiation Oncology, National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany; Translational Radiooncology and Clinical Radiotherapy and Image-guided High Precision Radiotherapy, German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; GermanTranslational Radiooncology and Clinical Radiotherapy and Image-guided High Precision Radiotherapy, Helmholtz Association / Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany; School of Medicine, Technische Universität Dresden, Dresden, Germany.
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