Unveiling the dynamics and therapeutic potential of m6A methyltransferases and demethylases in liver diseases.

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Title: Unveiling the dynamics and therapeutic potential of m6A methyltransferases and demethylases in liver diseases.
Authors: Chen YN; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Zhu S; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Sun LJ; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Zhou RR; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Zheng R; Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, School of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China., Li XF; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China., Li LY; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Sun SJ; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Zhao YX; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Huang C; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Meng XM; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Zhang L; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China., Lv XW; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China., Wang H; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Chen X; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China., Li J; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.
Source: International journal of biological sciences [Int J Biol Sci] 2025 Oct 01; Vol. 21 (14), pp. 6252-6269. Date of Electronic Publication: 2025 Oct 01 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
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  Data: Unveiling the dynamics and therapeutic potential of m<superscript>6</superscript>A methyltransferases and demethylases in liver diseases.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YN%22">Chen YN</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Zhu+S%22">Zhu S</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Sun+LJ%22">Sun LJ</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Zhou+RR%22">Zhou RR</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Zheng+R%22">Zheng R</searchLink>; Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, School of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China.<br /><searchLink fieldCode="AU" term="%22Li+XF%22">Li XF</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Li+LY%22">Li LY</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Sun+SJ%22">Sun SJ</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Zhao+YX%22">Zhao YX</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Meng+XM%22">Meng XM</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Lv+XW%22">Lv XW</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, The Third Affiliated Hospital, School of Pharmacy, Anhui Medical University, Hefei 230032, China.; The Key Laboratory of Anti-inflammatory and Immune Medicines, Anhui Medical University, Ministry of Education, Hefei 230032, China.; Institute for Liver Diseases of Anhui Medical University, ILD-AMU, Anhui Medical University, Hefei 230032, China.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2025 Oct 01; Vol. 21 (14), pp. 6252-6269. <i>Date of Electronic Publication: </i>2025 Oct 01 (<i>Print Publication: </i>2025).
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