Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.
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| Title: | Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma. |
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| Authors: | Rebhun RB; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Cruz SM; Division of Surgical Oncology, Department of Surgery, University of California, Davis/Sacramento, CA, United States., York D; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Mazcko CN; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States., Razmara AM; Division of Surgical Oncology, Department of Surgery, University of California, Davis/Sacramento, CA, United States., Patkar S; Artificial Intelligence Resource, Molecular Imaging Branch, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States., Judge SJ; Division of Surgical Oncology, Department of Surgery, University of California, Davis/Sacramento, CA, United States., Sholevar CJ; Division of Surgical Oncology, Department of Surgery, University of California, Davis/Sacramento, CA, United States., Shah RK; Departments of Medicine (Hematology and Oncology) and Microbiology & Immunology, Medical College of Wisconsin, Milwaukee, WI, United States., Zamora AE; Departments of Medicine (Hematology and Oncology) and Microbiology & Immunology, Medical College of Wisconsin, Milwaukee, WI, United States., Al-Nadaf S; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Vail DM; Department of Medical Sciences, School of Veterinary Medicine, and The Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI, United States., Fan TM; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, and Cancer Center at Illinois, University of Illinois, Urbana, IL, United States., Burton JH; Department of Clinical Sciences, Colorado State University College of Veterinary Medicine, Fort Collins, CO, United States., Luker ME; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Skorupski KA; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Lejeune AT; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Woolard K; Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States., Stewart SL; Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, Davis, CA, United States., Sparger EE; Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States., Young J; Veterinary Center for Clinical Trials, Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States., Cohen-Davidyan T; Veterinary Center for Clinical Trials, Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States., Huang E; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Rockville, MD, United States., Beck JA; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States., Murphy WJ; Department of Dermatology, University of California, Davis/Sacramento, Davis, CA, United States., Kent MS; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., Culp WTN; Department of Surgical and Radiological Sciences, University of California, Davis, Davis, CA, United States., LeBlanc AK; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States., Canter RJ; Division of Surgical Oncology, Department of Surgery, University of California, Davis/Sacramento, CA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Oct 23; Vol. 16, pp. 1672790. Date of Electronic Publication: 2025 Oct 23 (Print Publication: 2025). |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Multicenter Study |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1672790 |
