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Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis.

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Title: Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis.
Authors: Guo JC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan., Lin PS; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Shau WY; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan., Shao YY; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051., Kuo HY; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051., Chen CL; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan., Hsu CH; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051. chihhunghsu@ntu.edu.tw.
Source: Esophagus : official journal of the Japan Esophageal Society [Esophagus] 2026 Jan; Vol. 23 (1), pp. 25-36. Date of Electronic Publication: 2025 Nov 10.
Publication Type: Journal Article; Meta-Analysis; Systematic Review
Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 101206627 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-9067 (Electronic) Linking ISSN: 16129059 NLM ISO Abbreviation: Esophagus Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Guo+JC%22">Guo JC</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PS%22">Lin PS</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shau+WY%22">Shau WY</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shao+YY%22">Shao YY</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051.<br /><searchLink fieldCode="AU" term="%22Kuo+HY%22">Kuo HY</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051.<br /><searchLink fieldCode="AU" term="%22Chen+CL%22">Chen CL</searchLink>; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CH%22">Hsu CH</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. chihhunghsu@ntu.edu.tw.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, No.1, Section 1, Jen Ai Road, Taipei, Taiwan, 10051. chihhunghsu@ntu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101206627%22">Esophagus : official journal of the Japan Esophageal Society</searchLink> [Esophagus] 2026 Jan; Vol. 23 (1), pp. 25-36. <i>Date of Electronic Publication: </i>2025 Nov 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>101206627 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1612-9067 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216129059%22">16129059 </searchLink><i>NLM ISO Abbreviation: </i>Esophagus <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10388-025-01167-y
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        Text: English
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      – TitleFull: Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis.
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              Text: 2026 Jan
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            – TitleFull: Esophagus : official journal of the Japan Esophageal Society
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