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A Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of a Folate Receptor Alpha Vaccine in Patients with Triple-Negative Breast Cancer.

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Title: A Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of a Folate Receptor Alpha Vaccine in Patients with Triple-Negative Breast Cancer.
Authors: Knutson KL; Department of Immunology, Mayo Clinic, Jacksonville, Florida.; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida., Abu-Fares H; Department of Immunology, Mayo Clinic, Jacksonville, Florida., Keating P; Department of Biological Sciences, Florida Atlantic University, Boca Raton, Florida., Block MS; Department of Oncology, Mayo Clinic, Rochester, Minnesota.; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Norton N; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida., Erskine CL; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Cogen D; Department of Immunology, Mayo Clinic, Jacksonville, Florida., Assad H; Karmanos Cancer Institute, Detroit, Michigan., Graff SL; Research Medical Center, Kansas City, Missouri., Hamilton EP; Sarah Cannon Research Institute, Nashville, Tennessee., Han HS; Moffitt Cancer Center, Tampa, Florida., McIntyre KJ; Texas Oncology, Dallas, Texas., Nassar A; Department of Pathology and Laboratory Medicine, Mayo Clinic, Jacksonville, Florida., Sparano JA; Montefiore Medical Center, Bronx, New York., Tiersten A; Mount Sinai Hospital, New York, New York., Tkaczuk KH; University of Maryland, Baltimore, Maryland., Ward PJ; Oncology Hematology Care, Cincinnati, Ohio., Wilson G; TapImmune, Jacksonville, Florida., Garrett G; TapImmune, Jacksonville, Florida.; Marker Therapeutics, Houston, Texas., Kenney RT; TapImmune, Jacksonville, Florida.; Marker Therapeutics, Houston, Texas., Sharma P; University of Kansas Cancer Center, Westwood, Kansas.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Jan 06; Vol. 32 (1), pp. 106-117.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of a Folate Receptor Alpha Vaccine in Patients with Triple-Negative Breast Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Knutson+KL%22">Knutson KL</searchLink>; Department of Immunology, Mayo Clinic, Jacksonville, Florida.; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Abu-Fares+H%22">Abu-Fares H</searchLink>; Department of Immunology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Keating+P%22">Keating P</searchLink>; Department of Biological Sciences, Florida Atlantic University, Boca Raton, Florida.<br /><searchLink fieldCode="AU" term="%22Block+MS%22">Block MS</searchLink>; Department of Oncology, Mayo Clinic, Rochester, Minnesota.; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Norton+N%22">Norton N</searchLink>; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Erskine+CL%22">Erskine CL</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Cogen+D%22">Cogen D</searchLink>; Department of Immunology, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Assad+H%22">Assad H</searchLink>; Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Graff+SL%22">Graff SL</searchLink>; Research Medical Center, Kansas City, Missouri.<br /><searchLink fieldCode="AU" term="%22Hamilton+EP%22">Hamilton EP</searchLink>; Sarah Cannon Research Institute, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Han+HS%22">Han HS</searchLink>; Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22McIntyre+KJ%22">McIntyre KJ</searchLink>; Texas Oncology, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Nassar+A%22">Nassar A</searchLink>; Department of Pathology and Laboratory Medicine, Mayo Clinic, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Sparano+JA%22">Sparano JA</searchLink>; Montefiore Medical Center, Bronx, New York.<br /><searchLink fieldCode="AU" term="%22Tiersten+A%22">Tiersten A</searchLink>; Mount Sinai Hospital, New York, New York.<br /><searchLink fieldCode="AU" term="%22Tkaczuk+KH%22">Tkaczuk KH</searchLink>; University of Maryland, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Ward+PJ%22">Ward PJ</searchLink>; Oncology Hematology Care, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Wilson+G%22">Wilson G</searchLink>; TapImmune, Jacksonville, Florida.<br /><searchLink fieldCode="AU" term="%22Garrett+G%22">Garrett G</searchLink>; TapImmune, Jacksonville, Florida.; Marker Therapeutics, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kenney+RT%22">Kenney RT</searchLink>; TapImmune, Jacksonville, Florida.; Marker Therapeutics, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sharma+P%22">Sharma P</searchLink>; University of Kansas Cancer Center, Westwood, Kansas.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2026 Jan 06; Vol. 32 (1), pp. 106-117.
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  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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