Pt(IV) Prodrugs Bearing Sunitinib-Derived Ligands Display Exceptional Anticancer Activity against Renal Cell Carcinoma When Compared to Conventional Platinum Chemotherapy.
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| Title: | Pt(IV) Prodrugs Bearing Sunitinib-Derived Ligands Display Exceptional Anticancer Activity against Renal Cell Carcinoma When Compared to Conventional Platinum Chemotherapy. |
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| Authors: | Beirne DF; Department of Chemistry, Maynooth University, Maynooth W23 F2h6, Ireland., Arakelyan J; Department of Chemistry, City University of Hong Kong, Hong Kong SAR, China., Forner M; Universita' di Padova, Dipartimento di Scienze Del Farmaco, Padova 35131, Italy., Choe HJ; Department of Chemistry, City University of Hong Kong, Hong Kong SAR, China., Kriukov K; Department of Chemistry, City University of Hong Kong, Hong Kong SAR, China., Dempsey E; Department of Chemistry, Maynooth University, Maynooth W23 F2h6, Ireland.; Kathleen Londsdale Institute for Human Health Research, Maynooth University, Maynooth W23 F2h6 Ireland., Gandin V; Universita' di Padova, Dipartimento di Scienze Del Farmaco, Padova 35131, Italy., Velasco-Torrijos T; Department of Chemistry, Maynooth University, Maynooth W23 F2h6, Ireland.; Kathleen Londsdale Institute for Human Health Research, Maynooth University, Maynooth W23 F2h6 Ireland., Babak MV; Department of Chemistry, City University of Hong Kong, Hong Kong SAR, China., Montagner D; Department of Chemistry, Maynooth University, Maynooth W23 F2h6, Ireland.; Kathleen Londsdale Institute for Human Health Research, Maynooth University, Maynooth W23 F2h6 Ireland. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2025 Nov 27; Vol. 68 (22), pp. 24294-24304. Date of Electronic Publication: 2025 Nov 10. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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