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Novel PEEK fabrication using fused strand deposition reduces inflammation and enhances MSC differentiation promoting bone growth and implant osseointegration.

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Title: Novel PEEK fabrication using fused strand deposition reduces inflammation and enhances MSC differentiation promoting bone growth and implant osseointegration.
Authors: Cohen DJ; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Deng J; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Reith TM; Curiteva Inc., Huntsville, AL, USA., Sabalewski EL; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Pestov D; Nanomaterials Core Characterization Facility, Virginia Commonwealth University, Richmond, VA, USA., Dillon JT; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Jawad AY; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Slosar PJ; PS/md Consulting, Park City, UT, USA., Foley KT; Department of Neurosurgery, Semmes-Murphey Clinic and University of Tennessee Health Science Center, Memphis, TN, USA., Dryer RF; Central Texas Spine Institute, Austin, TX, USA., Bassett TD; Southeastern Spine Specialists, Tuscaloosa, AL, USA., Harrod CC; The Spine Center of Louisiana, Baton Rouge, LA, USA., Verrelli BC; School of Life Sciences and Sustainability, Virginia Commonwealth University, Richmond, VA, USA., Bertino MF; Department of Physics, Virginia Commonwealth University, Richmond, VA, USA., Erbe EM; Curiteva Inc., Huntsville, AL, USA., Schwartz Z; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA., Boyan BD; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: bboyan@vcu.edu.
Source: Biomaterials [Biomaterials] 2026 May; Vol. 328, pp. 123833. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Cohen+DJ%22">Cohen DJ</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Deng+J%22">Deng J</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Reith+TM%22">Reith TM</searchLink>; Curiteva Inc., Huntsville, AL, USA.<br /><searchLink fieldCode="AU" term="%22Sabalewski+EL%22">Sabalewski EL</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Pestov+D%22">Pestov D</searchLink>; Nanomaterials Core Characterization Facility, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Dillon+JT%22">Dillon JT</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Jawad+AY%22">Jawad AY</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Slosar+PJ%22">Slosar PJ</searchLink>; PS/md Consulting, Park City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Foley+KT%22">Foley KT</searchLink>; Department of Neurosurgery, Semmes-Murphey Clinic and University of Tennessee Health Science Center, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Dryer+RF%22">Dryer RF</searchLink>; Central Texas Spine Institute, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bassett+TD%22">Bassett TD</searchLink>; Southeastern Spine Specialists, Tuscaloosa, AL, USA.<br /><searchLink fieldCode="AU" term="%22Harrod+CC%22">Harrod CC</searchLink>; The Spine Center of Louisiana, Baton Rouge, LA, USA.<br /><searchLink fieldCode="AU" term="%22Verrelli+BC%22">Verrelli BC</searchLink>; School of Life Sciences and Sustainability, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Bertino+MF%22">Bertino MF</searchLink>; Department of Physics, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Erbe+EM%22">Erbe EM</searchLink>; Curiteva Inc., Huntsville, AL, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+Z%22">Schwartz Z</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Boyan+BD%22">Boyan BD</searchLink>; Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: bboyan@vcu.edu.
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  Data: <searchLink fieldCode="JN" term="%228100316%22">Biomaterials</searchLink> [Biomaterials] 2026 May; Vol. 328, pp. 123833. <i>Date of Electronic Publication: </i>2025 Nov 04.
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              Text: 2026 May
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