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Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank.

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Title: Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank.
Authors: Sokolow R; Department of Bioengineering, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA., Bhattacharya A; Department of Bioengineering, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA., Kissas G; ETH AI Center, ETH Zurich, Zurich, Switzerland., Thompson EW; Department of Bioengineering, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Beeche C; Department of Bioengineering, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA., Swago S; Department of Bioengineering, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA., Zhang D; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Viswanadha M; Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Morse C; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Chirinos J; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Damrauer S; Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Verma A; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Perdikaris P; Department of Mechanical Engineering and Applied Mechanics, School of Engineering and Applied Sciences at The University of Pennsylvania, Philadelphia, PA, USA., Rader DJ; Department of Medicine, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA., Witschey WR; Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. witschey@pennmedicine.upenn.edu.; Department of Radiology, Advanced Cardiovascular Imaging Lab, 11-155 Perelman Center for Advanced Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. witschey@pennmedicine.upenn.edu.
Corporate Authors: Penn Medicine Biobank
Source: Scientific reports [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39203. Date of Electronic Publication: 2025 Nov 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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