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Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study.

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Title: Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study.
Authors: Li LL; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Wang RZ; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China., Wang Z; Department of Geriatrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China., Hu H; Department of Neurology, The Second Affiliated Hospital of Soochow University, Soochow 215004, China., Xu W; Department of Neurology, Qingdao Municipal Hospital Group, Qingdao 266000, China., Zhu L; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Sun Y; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China., Chen KL; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Chen SF; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., He XY; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Yuan MY; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Huang YY; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Liu XY; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China., Liu P; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China., Ye QY; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China., Wang J; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Ju ZZ; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai 200040, China., Zhang W; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China., Hu B; Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China., Guo Y; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Cao XY; Department of Neurology, The Third Hospital of Hebei Medical University, Hebei 050051, China., Li YX; Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China., Zuo CT; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai 200040, China., Cheng W; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China., Jiang T; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Tan L; Department of Neurology, Qingdao Municipal Hospital Group, Qingdao 266000, China., Chen XC; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China., Zhao QH; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Cui M; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China., Peng GP; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China., Xin JW; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China., Yu JT; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.
Source: Brain : a journal of neurology [Brain] 2026 Jun 03; Vol. 149 (6), pp. 1973-1985.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Li+LL%22">Li LL</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Wang+RZ%22">Wang RZ</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Geriatrics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.<br /><searchLink fieldCode="AU" term="%22Hu+H%22">Hu H</searchLink>; Department of Neurology, The Second Affiliated Hospital of Soochow University, Soochow 215004, China.<br /><searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Department of Neurology, Qingdao Municipal Hospital Group, Qingdao 266000, China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China.<br /><searchLink fieldCode="AU" term="%22Chen+KL%22">Chen KL</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Chen+SF%22">Chen SF</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22He+XY%22">He XY</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Yuan+MY%22">Yuan MY</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Huang+YY%22">Huang YY</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Liu+XY%22">Liu XY</searchLink>; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China.<br /><searchLink fieldCode="AU" term="%22Liu+P%22">Liu P</searchLink>; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China.<br /><searchLink fieldCode="AU" term="%22Ye+QY%22">Ye QY</searchLink>; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Ju+ZZ%22">Ju ZZ</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.<br /><searchLink fieldCode="AU" term="%22Hu+B%22">Hu B</searchLink>; Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Cao+XY%22">Cao XY</searchLink>; Department of Neurology, The Third Hospital of Hebei Medical University, Hebei 050051, China.<br /><searchLink fieldCode="AU" term="%22Li+YX%22">Li YX</searchLink>; Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Zuo+CT%22">Zuo CT</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Cheng+W%22">Cheng W</searchLink>; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.<br /><searchLink fieldCode="AU" term="%22Jiang+T%22">Jiang T</searchLink>; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Tan+L%22">Tan L</searchLink>; Department of Neurology, Qingdao Municipal Hospital Group, Qingdao 266000, China.<br /><searchLink fieldCode="AU" term="%22Chen+XC%22">Chen XC</searchLink>; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China.<br /><searchLink fieldCode="AU" term="%22Zhao+QH%22">Zhao QH</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Cui+M%22">Cui M</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.<br /><searchLink fieldCode="AU" term="%22Peng+GP%22">Peng GP</searchLink>; Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310031, China.<br /><searchLink fieldCode="AU" term="%22Xin+JW%22">Xin JW</searchLink>; Department of Neurology, Fujian Medical University Union Hospital, Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou 350402, China.<br /><searchLink fieldCode="AU" term="%22Yu+JT%22">Yu JT</searchLink>; Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai 200040, China.
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  Data: <searchLink fieldCode="JN" term="%220372537%22">Brain : a journal of neurology</searchLink> [Brain] 2026 Jun 03; Vol. 149 (6), pp. 1973-1985.
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        Value: 10.1093/brain/awaf427
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              Text: 2026 Jun 03
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