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Ultrafast crosslinking, strongly adhesive de novo protein hydrogels promote cartilage regeneration.

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Title: Ultrafast crosslinking, strongly adhesive de novo protein hydrogels promote cartilage regeneration.
Authors: Nie K; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK., Fan Z; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK., Sun W; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Department of Orthopedics, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, 310058, China., Wu B; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK., Zhou S; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Zhao H; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Ou J; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Ji T; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Tian J; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Wei W; Department of Orthopedics, Center for Regeneration and Aging Medicine, Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China., Ouyang H; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China., Hay DC; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Institute of Regeneration and Repair, Centre for Regenerative Medicine, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH16 4UU, UK., Huang W; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK.; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; State Key Laboratory of Biobased Transportation Fuel Technology, Zhejiang University, Hangzhou, 310027, China.; Biomedical and Health Translational Research Centre of Zhejiang Province, Zhejiang University, Hangzhou, 310003, China.
Source: Bioactive materials [Bioact Mater] 2025 Oct 27; Vol. 56, pp. 368-385. Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ke Ai Publishing Country of Publication: China NLM ID: 101685294 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-199X (Electronic) Linking ISSN: 2452199X NLM ISO Abbreviation: Bioact Mater Subsets: PubMed not MEDLINE
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  Data: Ultrafast crosslinking, strongly adhesive de novo protein hydrogels promote cartilage regeneration.
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  Data: <searchLink fieldCode="AU" term="%22Nie+K%22">Nie K</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK.<br /><searchLink fieldCode="AU" term="%22Fan+Z%22">Fan Z</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK.<br /><searchLink fieldCode="AU" term="%22Sun+W%22">Sun W</searchLink>; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Department of Orthopedics, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Ou+J%22">Ou J</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Ji+T%22">Ji T</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Tian+J%22">Tian J</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Wei+W%22">Wei W</searchLink>; Department of Orthopedics, Center for Regeneration and Aging Medicine, Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, 322000, China.<br /><searchLink fieldCode="AU" term="%22Ouyang+H%22">Ouyang H</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Hay+DC%22">Hay DC</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Institute of Regeneration and Repair, Centre for Regenerative Medicine, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH16 4UU, UK.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Centre for Regeneration and Cell Therapy, The Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Deanery of Biomedical Sciences, Edinburgh Medical School, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, EH8 9XD UK.; Department of Orthopedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China.; State Key Laboratory of Biobased Transportation Fuel Technology, Zhejiang University, Hangzhou, 310027, China.; Biomedical and Health Translational Research Centre of Zhejiang Province, Zhejiang University, Hangzhou, 310003, China.
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  Data: <searchLink fieldCode="JN" term="%22101685294%22">Bioactive materials</searchLink> [Bioact Mater] 2025 Oct 27; Vol. 56, pp. 368-385. <i>Date of Electronic Publication: </i>2025 Oct 27 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ke+Ai+Publishing%22">Ke Ai Publishing </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101685294 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2452-199X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222452199X%22">2452199X </searchLink><i>NLM ISO Abbreviation: </i>Bioact Mater <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.bioactmat.2025.10.009
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        Text: English
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