Improved biosynthesis of lactulose by a novel thermostable cellobiose-2-epimerase generated through semi-rational mutagenesis.

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Title: Improved biosynthesis of lactulose by a novel thermostable cellobiose-2-epimerase generated through semi-rational mutagenesis.
Authors: Zhong C; College of Pharmaceutical Science, Zhejiang University of Technology, Chaowang Road 18, Hangzhou, 310014, P. R. China.; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou, 310014, China., Ding W; College of Pharmaceutical Science, Zhejiang University of Technology, Chaowang Road 18, Hangzhou, 310014, P. R. China.; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou, 310014, China., Lin H; College of Pharmaceutical Science, Zhejiang University of Technology, Chaowang Road 18, Hangzhou, 310014, P. R. China.; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou, 310014, China., Huang J; College of Pharmaceutical Science, Zhejiang University of Technology, Chaowang Road 18, Hangzhou, 310014, P. R. China. huangjin979@zjut.edu.cn.; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou, 310014, China. huangjin979@zjut.edu.cn.
Source: World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2025 Nov 11; Vol. 41 (11), pp. 451. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9012472 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-0972 (Electronic) Linking ISSN: 09593993 NLM ISO Abbreviation: World J Microbiol Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-0972
DOI:10.1007/s11274-025-04683-2