Female Mice with HSD17B1 Inactivation Show Mild Hyperandrogenism without Notable Impact on Reproductive Function or Bone.

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Title: Female Mice with HSD17B1 Inactivation Show Mild Hyperandrogenism without Notable Impact on Reproductive Function or Bone.
Authors: Junnila A; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland., Petruk N; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland., Heikelä H; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland., Postila P; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland., Hakkarainen J; Organon R&D Finland, Turku FI-20520, Finland., Martinez-Nieto G; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland.; Turku Center for Disease Modeling, University of Turku, Turku FI-20520, Finland., Uceda-Rodriguez E; Department of Cell Biology, Physiology and Immunology, University of Cordoba, and Instituto Maimónides de Investigación Biomédica de Córdoba, 14071 Córdoba, Spain., Ruiz-Pino F; Department of Cell Biology, Physiology and Immunology, University of Cordoba, and Instituto Maimónides de Investigación Biomédica de Córdoba, 14071 Córdoba, Spain., Tena-Sempere M; Department of Cell Biology, Physiology and Immunology, University of Cordoba, and Instituto Maimónides de Investigación Biomédica de Córdoba, 14071 Córdoba, Spain., Ohlsson C; The Sahlgrenska Osteoporosis Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden., Sipilä P; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland.; Turku Center for Disease Modeling, University of Turku, Turku FI-20520, Finland., Heino TJ; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland., Määttä J; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland.; Turku Center for Disease Modeling, University of Turku, Turku FI-20520, Finland., Poutanen M; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku FI-20520, Finland.; The Sahlgrenska Osteoporosis Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden.
Source: Endocrinology [Endocrinology] 2025 Dec 05; Vol. 167 (1).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1945-7170
DOI:10.1210/endocr/bqaf167