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PI3K/mTORC2-RICTOR axis in early squamous non-small-cell lung cancer: genomics, molecular expression, and clinical relevance.

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Title: PI3K/mTORC2-RICTOR axis in early squamous non-small-cell lung cancer: genomics, molecular expression, and clinical relevance.
Authors: Pilotto S; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy., Belluomini L; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy., Monaca F; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Simbolo M; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy., Agostini A; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Mafficini A; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy., Golovco S; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy., Sperduti I; Biostatistics, IRCCS Regina Elena National Cancer Institute, Rome, Lazio, Italy., Vita E; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy., Stefani A; Università Cattolica del Sacro Cuore, Rome, Italy., Carbone C; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Piro G; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Ferrara MG; Università Cattolica del Sacro Cuore, Rome, Italy.; Thermo Fisher Scientific, Waltham, MA, USA., Lococo F; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Ludovini V; Division of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy., Chiari R; UOC Oncologia, AST Pesaro Urbino, Pesaro, Italy., Novello S; Thoracic Oncology Unit, San Luigi Hospital, University of Turin, Orbassano, Italy., Corbo V; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy., Milella M; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy., Scarpa A; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy., Tortora G; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy., Bria E; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Largo Francesco Vito, 1, Rome 00168, Italy.; Università Cattolica del Sacro Cuore, Rome, Italy Medical Oncology, Ospedale Isola Tiberina-Gemelli Isola, Rome, Italy.
Source: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2025 Nov 07; Vol. 17, pp. 17588359251370510. Date of Electronic Publication: 2025 Nov 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Sage Country of Publication: England NLM ID: 101510808 Publication Model: eCollection Cited Medium: Print ISSN: 1758-8340 (Print) Linking ISSN: 17588340 NLM ISO Abbreviation: Ther Adv Med Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: PI3K/mTORC2-RICTOR axis in early squamous non-small-cell lung cancer: genomics, molecular expression, and clinical relevance.
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  Data: <searchLink fieldCode="AU" term="%22Pilotto+S%22">Pilotto S</searchLink>; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Belluomini+L%22">Belluomini L</searchLink>; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Monaca+F%22">Monaca F</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Simbolo+M%22">Simbolo M</searchLink>; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Agostini+A%22">Agostini A</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mafficini+A%22">Mafficini A</searchLink>; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Golovco+S%22">Golovco S</searchLink>; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Sperduti+I%22">Sperduti I</searchLink>; Biostatistics, IRCCS Regina Elena National Cancer Institute, Rome, Lazio, Italy.<br /><searchLink fieldCode="AU" term="%22Vita+E%22">Vita E</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stefani+A%22">Stefani A</searchLink>; Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Carbone+C%22">Carbone C</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Piro+G%22">Piro G</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrara+MG%22">Ferrara MG</searchLink>; Università Cattolica del Sacro Cuore, Rome, Italy.; Thermo Fisher Scientific, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lococo+F%22">Lococo F</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ludovini+V%22">Ludovini V</searchLink>; Division of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Chiari+R%22">Chiari R</searchLink>; UOC Oncologia, AST Pesaro Urbino, Pesaro, Italy.<br /><searchLink fieldCode="AU" term="%22Novello+S%22">Novello S</searchLink>; Thoracic Oncology Unit, San Luigi Hospital, University of Turin, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Corbo+V%22">Corbo V</searchLink>; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Milella+M%22">Milella M</searchLink>; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Scarpa+A%22">Scarpa A</searchLink>; Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.; ARC-NET Applied Research on Cancer Center, University and Hospital Trust of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Tortora+G%22">Tortora G</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bria+E%22">Bria E</searchLink>; Comprehensive Cancer Center, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Largo Francesco Vito, 1, Rome 00168, Italy.; Università Cattolica del Sacro Cuore, Rome, Italy Medical Oncology, Ospedale Isola Tiberina-Gemelli Isola, Rome, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101510808%22">Therapeutic advances in medical oncology</searchLink> [Ther Adv Med Oncol] 2025 Nov 07; Vol. 17, pp. 17588359251370510. <i>Date of Electronic Publication: </i>2025 Nov 07 (<i>Print Publication: </i>2025).
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