Eye-Targeted A20 Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis.
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| Title: | Eye-Targeted A20 Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis. |
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| Authors: | Essayagh S; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Aridi T; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Turunen T; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Choi L; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Adam H; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Patel N; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Scali ST; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Fisher MD; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Skaf K; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Csizmadia E; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Brennan P; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Sadek A; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Skaf J; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Zhan M; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Hansen E; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Shamloo M; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., DeStefino NR; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Clermont AC; The Eye Unit, Joslin Diabetes Center, Boston, Massachusetts, USA., Angolano C; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA., Ferran C; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.; The Transplant Institute and the Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. |
| Source: | FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Nov 30; Vol. 39 (22), pp. e71226. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41222786 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Eye-Targeted A20 Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Essayagh+S%22">Essayagh S</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Aridi+T%22">Aridi T</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Turunen+T%22">Turunen T</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Choi+L%22">Choi L</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Adam+H%22">Adam H</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Patel+N%22">Patel N</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Scali+ST%22">Scali ST</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Fisher+MD%22">Fisher MD</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Skaf+K%22">Skaf K</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Csizmadia+E%22">Csizmadia E</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Brennan+P%22">Brennan P</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sadek+A%22">Sadek A</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Skaf+J%22">Skaf J</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Zhan+M%22">Zhan M</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+E%22">Hansen E</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shamloo+M%22">Shamloo M</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22DeStefino+NR%22">DeStefino NR</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Clermont+AC%22">Clermont AC</searchLink>; The Eye Unit, Joslin Diabetes Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Angolano+C%22">Angolano C</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ferran+C%22">Ferran C</searchLink>; Department of Surgery, The Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.; The Transplant Institute and the Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228804484%22">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</searchLink> [FASEB J] 2025 Nov 30; Vol. 39 (22), pp. e71226. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Federation+of+American+Societies+for+Experimental+Biology%22">Federation of American Societies for Experimental Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8804484 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-6860 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208926638%22">08926638 </searchLink><i>NLM ISO Abbreviation: </i>FASEB J <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41222786 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1096/fj.202500419R Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e71226 Titles: – TitleFull: Eye-Targeted A20 Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Essayagh S – PersonEntity: Name: NameFull: Aridi T – PersonEntity: Name: NameFull: Turunen T – PersonEntity: Name: NameFull: Choi L – PersonEntity: Name: NameFull: Adam H – PersonEntity: Name: NameFull: Patel N – PersonEntity: Name: NameFull: Scali ST – PersonEntity: Name: NameFull: Fisher MD – PersonEntity: Name: NameFull: Skaf K – PersonEntity: Name: NameFull: Csizmadia E – PersonEntity: Name: NameFull: Brennan P – PersonEntity: Name: NameFull: Sadek A – PersonEntity: Name: NameFull: Skaf J – PersonEntity: Name: NameFull: Zhan M – PersonEntity: Name: NameFull: Hansen E – PersonEntity: Name: NameFull: Shamloo M – PersonEntity: Name: NameFull: DeStefino NR – PersonEntity: Name: NameFull: Clermont AC – PersonEntity: Name: NameFull: Angolano C – PersonEntity: Name: NameFull: Ferran C IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 11 Text: 2025 Nov 30 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1530-6860 Numbering: – Type: volume Value: 39 – Type: issue Value: 22 Titles: – TitleFull: FASEB journal : official publication of the Federation of American Societies for Experimental Biology Type: main |
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