Study protocol for a multicenter, multinational prospective randomized controlled trial comparing outcomes in subjects with Gram-negative bacteremia who have blood culture evaluation using Fast Antibiotic Susceptibility Testing vs. standard of care testing: the FAST trial.
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| Title: | Study protocol for a multicenter, multinational prospective randomized controlled trial comparing outcomes in subjects with Gram-negative bacteremia who have blood culture evaluation using Fast Antibiotic Susceptibility Testing vs. standard of care testing: the FAST trial. |
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| Authors: | Banerjee R; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA. ritu.banerjee@vumc.org., Komarow L; The Biostatistics Center, George Washington University, Rockville, MD, USA., Li Y; The Biostatistics Center, George Washington University, Rockville, MD, USA., Wu Q; The Biostatistics Center, George Washington University, Rockville, MD, USA., Sanchez-Gonzalez L; The Biostatistics Center, George Washington University, Rockville, MD, USA., Mau D; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Abbenante E; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Schwager N; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Dodd A; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Souli M; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Geres HS; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Doernberg S; Department of Medicine, University of California, San Francisco, CA, USA., Greenwood-Quaintance K; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Evans SR; The Biostatistics Center, George Washington University, Rockville, MD, USA., Chambers HF; Department of Medicine, University of California, San Francisco, CA, USA., Fowler VG Jr; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA., Patel R; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. |
| Corporate Authors: | Antibacterial Resistance Leadership Group |
| Source: | Trials [Trials] 2025 Nov 12; Vol. 26 (1), pp. 500. Date of Electronic Publication: 2025 Nov 12. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1745-6215 |
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| DOI: | 10.1186/s13063-025-09228-4 |
