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Potential Antiviral Compounds from Hippeastrum puniceum Bulb Against Yellow Fever Virus: Bioassay-Guided Fractionation and In Silico Pharmacokinetic Analysis.

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Title: Potential Antiviral Compounds from Hippeastrum puniceum Bulb Against Yellow Fever Virus: Bioassay-Guided Fractionation and In Silico Pharmacokinetic Analysis.
Authors: Flores-Souza E; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Caldeira ASP; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Pacca-Mazaro CC; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., de Souza TVM; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Acácio TM; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Barbosa EC; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Tavares NC; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Calzavara-Silva CE; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Zani CL; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., Pires DEV; School of Computing and Information Systems, The University of Melbourne, Melbourne 3010, Australia., Alves TMA; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil., de Oliveira JG; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
Source: Molecules (Basel, Switzerland) [Molecules] 2025 Oct 22; Vol. 30 (21). Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Potential Antiviral Compounds from Hippeastrum puniceum Bulb Against Yellow Fever Virus: Bioassay-Guided Fractionation and In Silico Pharmacokinetic Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Flores-Souza+E%22">Flores-Souza E</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Caldeira+ASP%22">Caldeira ASP</searchLink>; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Pacca-Mazaro+CC%22">Pacca-Mazaro CC</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Souza+TVM%22">de Souza TVM</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Acácio+TM%22">Acácio TM</searchLink>; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Barbosa+EC%22">Barbosa EC</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Tavares+NC%22">Tavares NC</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Calzavara-Silva+CE%22">Calzavara-Silva CE</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Zani+CL%22">Zani CL</searchLink>; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22Pires+DEV%22">Pires DEV</searchLink>; School of Computing and Information Systems, The University of Melbourne, Melbourne 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Alves+TMA%22">Alves TMA</searchLink>; Grupo de Pesquisa de Química de Produtos Naturais Bioativos, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+JG%22">de Oliveira JG</searchLink>; Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto René Rachou-Fiocruz Minas, Belo Horizonte 30190-002, MG, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22100964009%22">Molecules (Basel, Switzerland)</searchLink> [Molecules] 2025 Oct 22; Vol. 30 (21). <i>Date of Electronic Publication: </i>2025 Oct 22.
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