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Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug-Placebo Differences.

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Title: Modulating Placebo Effects in Clinical Trials: Study Team Briefing to Optimize Drug-Placebo Differences.
Authors: Coenen M; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Bingel U; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences, University Hospital Essen, Essen, Germany., Soledad Berdaguer M; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Fuhrmann C; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Németh R; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Medical Biometrics, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Rengelshausen J; Institute for Occupational, Social and Environmental Medicine, Uniklinik RWTH Aachen, Aachen, Germany., Hartmann G; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Coch C; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.; Clinic and Policlinic for Neurosurgery, Leipzig, Germany., Schedlowski M; Institute of Medical Psychology and Behavioral Immunobiology, Center for Translational Neuro- and Behavioural Sciences, University Hospital Essen, Essen, Germany.; Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden.
Source: Clinical and translational science [Clin Transl Sci] 2025 Nov; Vol. 18 (11), pp. e70399.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Coenen+M%22">Coenen M</searchLink>; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bingel+U%22">Bingel U</searchLink>; Department of Neurology, Center for Translational Neuro- and Behavioural Sciences, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Soledad+Berdaguer+M%22">Soledad Berdaguer M</searchLink>; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Fuhrmann+C%22">Fuhrmann C</searchLink>; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Németh+R%22">Németh R</searchLink>; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Medical Biometrics, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Rengelshausen+J%22">Rengelshausen J</searchLink>; Institute for Occupational, Social and Environmental Medicine, Uniklinik RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+G%22">Hartmann G</searchLink>; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Coch+C%22">Coch C</searchLink>; Clinical Study Core Unit, Study Center Bonn (SZB), University Hospital Bonn, Bonn, Germany.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.; Clinic and Policlinic for Neurosurgery, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Schedlowski+M%22">Schedlowski M</searchLink>; Institute of Medical Psychology and Behavioral Immunobiology, Center for Translational Neuro- and Behavioural Sciences, University Hospital Essen, Essen, Germany.; Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden.
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              Text: 2025 Nov
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