A framework to determine active neurons and networks within the mouse brain reveals how brain activity changes over the course of the day.

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Title: A framework to determine active neurons and networks within the mouse brain reveals how brain activity changes over the course of the day.
Authors: Sun G; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States., Mano T; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Computational Neuroethology Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Okinawa, Japan., Shi S; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; International Institute for Integrative Sleep Medicine (IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan., Li A; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States., Ode KL; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Rosi-Andersen A; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Pedron E; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Brown SA; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Ueda HR; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory of Synthetic Biology, RIKEN Biosystems Dynamics Research, Osaka, Japan.; Department of Systems Biology, Institute of Life Science, Kurume University, Fukuoka, Japan., Kompotis K; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Forger DB; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Gilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States.
Source: PLoS biology [PLoS Biol] 2025 Nov 13; Vol. 23 (11), pp. e3003472. Date of Electronic Publication: 2025 Nov 13 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
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  Data: A framework to determine active neurons and networks within the mouse brain reveals how brain activity changes over the course of the day.
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  Data: <searchLink fieldCode="AU" term="%22Sun+G%22">Sun G</searchLink>; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.<br /><searchLink fieldCode="AU" term="%22Mano+T%22">Mano T</searchLink>; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Computational Neuroethology Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Okinawa, Japan.<br /><searchLink fieldCode="AU" term="%22Shi+S%22">Shi S</searchLink>; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; International Institute for Integrative Sleep Medicine (IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.<br /><searchLink fieldCode="AU" term="%22Ode+KL%22">Ode KL</searchLink>; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Rosi-Andersen+A%22">Rosi-Andersen A</searchLink>; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pedron+E%22">Pedron E</searchLink>; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brown+SA%22">Brown SA</searchLink>; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ueda+HR%22">Ueda HR</searchLink>; Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory of Synthetic Biology, RIKEN Biosystems Dynamics Research, Osaka, Japan.; Department of Systems Biology, Institute of Life Science, Kurume University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kompotis+K%22">Kompotis K</searchLink>; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forger+DB%22">Forger DB</searchLink>; Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States.; Gilbert S. Omenn Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States.
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